Results 271 to 280 of about 71,583 (333)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, Volume 1, Issue 3, Page 322-358, December 2025.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Isorhythmic atrioventricular dissociation during anaesthesia in a cat

Veterinary Record Case Reports, Volume 13, Issue 4, December 2025.
Abstract A 10‐year‐old, male, neutered domestic shorthair cat with suspected hypertrophic cardiomyopathy was referred for cystotomy to remove uroliths present in its urinary bladder. Fifteen minutes after induction of general anaesthesia, atrioventricular dissociation was noted on the electrocardiogram with similar atrial and ventricular firing rates ...
Gemma Padrosa Sala, Cristian Cabellos Clemente, Paul Wotton, Frane Ivasovic   +3 more
wiley   +1 more source

Implantation of new VR leadless pacemaker in a 4-year-old, 16-kg patient with complete atrioventricular block. [PDF]

HeartRhythm Case Rep
Greco A, Chipa F, Cruzalegui J, Tolosana JM, Moscoso BA, Sarquella-Brugada G.   +5 more
europepmc   +1 more source

Cardiology for dummies [PDF]

, 2011
van Loon, Gunther
core  

Aged Zebrafish as a Spontaneous Model of Cardiac Valvular Disease

Aging Cell, Volume 24, Issue 12, December 2025.
Natural ageing in zebrafish results in spontaneous development of valvular degeneration in both the atrioventricular (AV) and bulboventricular (BV) valves. Aged zebrafish valves are larger and exhibit cystic regions, immune cell infiltration, early osteoblast differentiation and increased regurgitation.
Laura Bevan, Jessica Radford, Helena Urquijo, Joseph Carr, Alice Etheridge, Stephen Cross, Melanie Hezzell, Rebecca J. Richardson   +7 more
wiley   +1 more source

Ulcerative colitis increases the risk of atrioventricular block: evidence from a Mendelian randomized analysis. [PDF]

Sci Rep
Shu W, Huang G.
europepmc   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, Volume 58, Issue 12, December 2025.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

Transient Third-Degree Atrioventricular Block in a Dog with Addisonian Crisis. [PDF]

Vet Sci
Pașca PM, Solcan G, Blageanu A, Lăcătuș CM, Peștean PC, Stancu CA, Baisan AR.   +6 more
europepmc   +1 more source