Results 91 to 100 of about 1,369,250 (321)

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

open access: yesEpilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus   +7 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Clinical and Electrophysiological Predictors of Ventriculoatrial Conduction in Patients under Evaluation for Ventricular Tachyarrhythmia

open access: yesJournal of Tehran University Heart Center, 2010
Background: Ventriculoatrial (VA) conduction has an important role in the initiation and maintenance of some arrhythmias. The aim of this study was to evaluate whether clinical and electrophysiological parameters of atrioventricular (AV) conduction can ...
Mohammad Reza Dehghani   +2 more
doaj  

Sphingosine‐1‐Phosphate Receptor Modulators for the Treatment of Ulcerative Colitis: A Narrative Review Focusing on Safety

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Ulcerative colitis is a chronic immune‐mediated inflammatory disease of the colon that causes considerable morbidity and increases the risk of colorectal cancer. Several targeted therapies have been developed for moderate‐to‐severe ulcerative colitis, significantly improving its management.
Massimo C. Fantini   +4 more
wiley   +1 more source

Electrophysiological differences of randomized deep sedation with dexmedetomidine versus propofol

open access: yesBMC Anesthesiology
Background Dexmedetomidine and propofol are common sedatives in intensive care units and for interventional procedures. Both may compromise sinus node function and atrioventricular conduction.
Helge Servatius   +12 more
doaj   +1 more source

Rate-Control or Rhythm-Contol: Where do we stand? [PDF]

open access: yes, 2005
Atrial fibrillation is the most common sustained rhythm disturbance and its prevalence is increasing worldwide due to the progressive aging of the population.
A, Dello Russo   +6 more
core   +1 more source

Exponential distribution of long heart beat intervals during atrial fibrillation and their relevance for white noise behaviour in power spectrum [PDF]

open access: yes, 2006
The statistical properties of heart beat intervals of 130 long-term surface electrocardiogram recordings during atrial fibrillation (AF) are investigated.
A. Bollmann   +34 more
core   +2 more sources

Serious outcomes among emergency department patients with presyncope: A systematic review

open access: yesAcademic Emergency Medicine, EarlyView.
Abstract Background Syncope is transient loss of consciousness, and in presyncope, patients experience same prodromal symptoms without losing consciousness. While studies have extensively reported the risk of serious outcome among emergency department (ED) syncope, the outcome for patients with presyncope and their management are not well studied.
Hadi Mirfazaelian   +4 more
wiley   +1 more source

Automatic Mode Switching in Atrial Fibrillation [PDF]

open access: yes, 2005
Automatic mode switching (AMS) algorithms were designed to prevent tracking of atrial tachyarrhythmias (ATA) or other rapidly occurring signals sensed by atrial channels, thereby reducing the adverse hemodynamic and symptomatic consequences of a rapid ...
Antonio De, Simone   +2 more
core  

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