Results 141 to 150 of about 34,555 (299)

MADR-Net: multi-level attention dilated residual neural network for segmentation of medical images

open access: yesScientific Reports
Medical image segmentation has made a significant contribution towards delivering affordable healthcare by facilitating the automatic identification of anatomical structures and other regions of interest.
Keerthiveena Balraj   +4 more
doaj   +1 more source

Comparative Efficacy of Continuous Positive Airway Pressure and Mandibular Advancement Devices in the Treatment of Obstructive Sleep Apnea: A Systematic Review

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Obstructive Sleep Apnea is a prevalent condition linked to various health issues, including cardiovascular disease and cognitive decline. This systematic review evaluates the comparative efficacy and patient adherence of two primary treatment modalities: Continuous Positive Airway Pressure and Mandibular Advancement Devices.
Gianna Dipalma   +9 more
wiley   +1 more source

Advances in cardiac devices and bioelectronics augmented with artificial intelligence

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark   +3 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

Enhancing stroke risk stratification in atrial fibrillation through non‐Newtonian blood modelling and Gaussian process emulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Non‐Newtonian modelling and GPEs for stroke risk in atrial fibrilation patients. Abstract Atrial fibrillation (AF) is the most common heart arrhythmia, linked to a five‐fold increase in stroke risk. The left atrial appendage (LAA), prone to blood stasis, is a common thrombus formation site in AF patients.
Paolo Melidoro   +12 more
wiley   +1 more source

Gap junctional and ephaptic coupling in cardiac electrical propagation: homocellular and heterocellular perspectives

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Intricate cellular electrical coupling networks in the heart. Various cell types couple the central cardiomyocyte through gap junctional contacts, with the exception of neurons. Whether ephaptic coupling (EpC) occurs in homocellular or heterocellular contexts beyond cardiomyocyte–cardiomyocyte interactions remains unclear ...
Xiaobo Wu   +2 more
wiley   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo   +5 more
wiley   +1 more source

Editorial: The architecture of the human sinus node. [PDF]

open access: yesFront Med (Lausanne)
Irurzun IM, Goin JC, Defeo MM.
europepmc   +1 more source

Electrophysiological characterization of pre‐adolescents born with intrauterine growth restriction: insights from clinical and computational data

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Depolarization and repolarization duration analysis was conducted in preadolescent groups with IUGR and controls using a 12‐lead ECG. Principal component analysis was applied over the 12‐lead ECGs to generate spatially transformed leads better suited for robust ECG fiducial points detection.
Freddy L. Bueno‐Palomeque   +5 more
wiley   +1 more source

A deep learning‐enabled toolkit for the 3D segmentation of ventricular cardiomyocytes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend 3D cardiomyocyte segmentation enables comprehensive analyses of myocardial microstructure in health and disease; however, it is technically demanding. We present an open‐source toolkit for this task, which reduces challenges associated with sample preparation, image restoration, segmentation and proofreading.
Joachim Greiner   +6 more
wiley   +1 more source

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