Results 151 to 160 of about 1,985,753 (253)

The multifaceted roles of ketones in physiology

Experimental Physiology, EarlyView.
Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili, Kunyan Yang, Magnus J. Stenlund, John R. Ussher   +3 more
wiley   +1 more source

Indoor thermal nonuniformity of atrium-centered public building: Monitoring and diagnosis for energy saving

Case Studies in Thermal Engineering
Heating ventilation and air conditioning system accounts for over one third of building energy usage, especially for public buildings due to large indoor heat source and high ventilation and thermal comfort requirement compared to residential buildings ...
Zhineng Jin, Yin Zhang, Hongli Sun, Meng Han, Yanhong Zheng, Ying Zhao, Wenyang Han, Menglong Zhang   +7 more
doaj   +1 more source

Advances in cardiac devices and bioelectronics augmented with artificial intelligence

The Journal of Physiology, EarlyView.
Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark, Eric Rytkin, Andrei Alexandru Mircea, Igor R. Efimov   +3 more
wiley   +1 more source

Arkitim och Atriumhusene i Furubergveien - Om arkitektteamet, bostäder, rymliga element och materialitet

, 2021
Uppsatsen är strukturerad runt fyra delfrågeställningar som har som syfte att belysa arkitektteamet Arkitim som etablerades i 1962 i Hamar. Teamet bestod av de fyra arkitekterna Finn Bø, Per Torp Ildahl, Are Vesterlid och Hans Østerhaug samt interiörarkitekten Edvin Helseth.
openaire   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Enhancing stroke risk stratification in atrial fibrillation through non‐Newtonian blood modelling and Gaussian process emulation

The Journal of Physiology, EarlyView.
Abstract figure legend Non‐Newtonian modelling and GPEs for stroke risk in atrial fibrilation patients. Abstract Atrial fibrillation (AF) is the most common heart arrhythmia, linked to a five‐fold increase in stroke risk. The left atrial appendage (LAA), prone to blood stasis, is a common thrombus formation site in AF patients.
Paolo Melidoro, Abdel Rahman Amr Sultan, Ahmed Qureshi, Magdi H. Yacoub, Khalil L. Elkhodary, Gregory Y. H. Lip, Natalie Montarello, Nishant Lahoti, Ronak Rajani, Magdalena Klis, Steven E. Williams, Oleg Aslanidi, Adelaide De Vecchi   +12 more
wiley   +1 more source

Gap junctional and ephaptic coupling in cardiac electrical propagation: homocellular and heterocellular perspectives

The Journal of Physiology, EarlyView.
Abstract figure legend Intricate cellular electrical coupling networks in the heart. Various cell types couple the central cardiomyocyte through gap junctional contacts, with the exception of neurons. Whether ephaptic coupling (EpC) occurs in homocellular or heterocellular contexts beyond cardiomyocyte–cardiomyocyte interactions remains unclear ...
Xiaobo Wu, Laura Beth Payne, Robert G. Gourdie   +2 more
wiley   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

The Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo, Zachary D. Long, Arie O. Verkerk, Jose M. Ferrero, T. Alexander Quinn, Jose F. Rodriguez Matas   +5 more
wiley   +1 more source

Computational modelling of the impact of anatomical changes on ECGs in left ventricular hypertrophy

The Journal of Physiology, EarlyView.
Abstract figure legend Eccentric and concentric left ventricular hypertrophy distinctly alter 12‐lead ECG signals. Eccentric hypertrophy predominantly increases voltages in the precordial leads, whereas concentric hypertrophy affects voltages across all leads in a variable manner.
Mohammadreza Kariman, Karli Gillette, Matthias A. F. Gsell, Anton J. Prassl, Gernot Plank, Christoph M. Augustin   +5 more
wiley   +1 more source

Electrophysiological characterization of pre‐adolescents born with intrauterine growth restriction: insights from clinical and computational data

The Journal of Physiology, EarlyView.
Abstract figure legend Depolarization and repolarization duration analysis was conducted in preadolescent groups with IUGR and controls using a 12‐lead ECG. Principal component analysis was applied over the 12‐lead ECGs to generate spatially transformed leads better suited for robust ECG fiducial points detection.
Freddy L. Bueno‐Palomeque, Ernesto Zacur, Esther Pueyo, Fàtima Crispi, Pablo Laguna, Ana Mincholé   +5 more
wiley   +1 more source