Results 161 to 170 of about 1,985,753 (253)

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications

The Journal of Physiology, EarlyView.
Abstract figure legend Summary of key aspects of atrial fibrosis in atrial fibrillation, highlighting atrial fibrosis as a hallmark of atrial fibrillation (AF). (1) Different types of fibrosis (blue), illustrating reparative and reactive fibrosis; (2) fibrosis detection techniques (green), illustrating late gadolinium enhancement cardiac magnetic ...
Caterina Vidal Horrach, Laura Bevis, Cynthia Nwanna, Alexander M Zolotarev, Mahmoud Ehnesh, Semhar Biniam Misghina, Sayed Al‐Aidarous, Shohreh Honarbakhsh, Caroline H. Roney   +8 more
wiley   +1 more source

Edoxaban‐induced enterocolitis: The first case report demonstrating distinct endoscopic and histological features

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Direct oral anticoagulants (DOACs), including edoxaban, are widely used for stroke prevention in atrial fibrillation and venous thromboembolism. While gastrointestinal bleeding and diarrhea are recognized adverse effects, DOAC‐induced enterocolitis has not been established as a distinct clinical entity.
Katsuya Endo, Jun Yamada, Tomofumi Katayama, Yuki Yoshino, Daisuke Fukushi, Akinobu Koiwai, Takayuki Kogure, Morihisa Hirota, Kennichi Satoh   +8 more
wiley   +1 more source

Progress in Pharmacogenomics Implementation in the United States: Barrier Erosion and Remaining Challenges

Clinical Pharmacology &Therapeutics, Volume 118, Issue 4, Page 778-789, October 2025.
Barriers to incorporating pharmacogenetics into routine clinical practice in the United States are well documented. Initial surveys by the Clinical Pharmacogenetics Implementation Consortium (CPIC) in 2009 and 2010 identified barriers across four key domains that have hindered the widespread adoption of clinical pharmacogenetic testing.
D. Max Smith, Michael P. Douglas, Christina L. Aquilante, Patricia A. Deverka, Beth Devine, Henry M. Dunnenberger, Philip E. Empey, Daniel L. Hertz, Andrew A. Monte, Ann M. Moyer, Jai N. Patel, Victoria M. Pratt, Loren Saulsberry, Stuart A. Scott, Deepak Voora, Erica L. Woodahl, Michelle Whirl‐Carrillo, Akinyemi Oni‐Orisan, on behalf of the Pharmacogenomics Global Research Network (PGRN) Publications Committee   +18 more
wiley   +1 more source

ARHITEKTURNO IZVEDBENI VIDIKI: PROJEKT ATRIJSKE HIŠE

, 2011
The subject matter of the diploma paper is the atrium house. The origin and development of atrium houses through various periods of time until today are presented on the basis of researched literature. The main characteristics, advantages and disadvantages of an atrium house around the world and in Slovenia are presented together with various examples ...
openaire   +1 more source

Genetic insights into congenital heart disease: Prevalence, aetiology and clinical implications

Clinical and Translational Discovery, Volume 5, Issue 5, October 2025.
The review synthesizes current knowledge on the genetic underpinnings of congenital heart disease, highlighting how modern genomic technologies enhance understanding of CHD pathogenesis and enable earlier diagnosis. We demonstrate how these genetic insights translate to improved clinical care, risk assessment, and genetic counseling for affected ...
Yuan Yuan, Yi Jia, Shasha Peng, Shuru Zhao, Kang Dong, Yuruo Hu, Zicheng Zhao, Xiaofei Jiang, Zhe Zhang   +8 more
wiley   +1 more source

Dreamy Dwellings: How the Sleep Environment Affects Sleep Health in Adults—A Narrative Review

Lifestyle Medicine, Volume 6, Issue 4, October 2025.
ABSTRACT Sufficient high‐quality, well‐timed sleep is essential to health and physical, cognitive and emotional functions. Historically, environmental factors such as threats from other beings have likely constrained sleep. Newer sources of sleep disruption include modern work schedules, climate change, light pollution and noise pollution.
Gregory David Maxwell Potter, Gregory J. Grosicki, Grant M. Tinsley, Thomas R. Wood, Dan Garner, Andrew J. Galpin   +5 more
wiley   +1 more source

Real‐time cardiac cine MRI: A comparison of a diffusion probabilistic model with alternative state‐of‐the‐art image reconstruction techniques for undersampled spiral acquisitions

Magnetic Resonance in Medicine, Volume 94, Issue 4, Page 1731-1749, October 2025.
Abstract Purpose Electrocardiogram (ECG)‐gated cine imaging in breath‐hold enables high‐quality diagnostics in most patients but can be compromised by arrhythmia and inability to hold breath. Real‐time cardiac MRI offers faster and robust exams without these limitations.
Oliver Schad, Julius Frederik Heidenreich, Nils Petri, Jonas Kleineisel, Simon Sauer, Thorsten Alexander Bley, Peter Nordbeck, Bernhard Petritsch, Tobias Wech   +8 more
wiley   +1 more source

Current progress of digital twin construction using medical imaging

Journal of Applied Clinical Medical Physics, Volume 26, Issue 9, September 2025.
Abstract Medical imaging is fundamental to digital twin technology, enabling patient‐specific virtual models of anatomy and physiology. By integrating high‐resolution modalities (Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Positron Emission Tomography (PET), ultrasound) with computational frameworks, recent imaging advances now support ...
Feng Zhao, Yizhou Wu, Mingzhe Hu, Chih‐Wei Chang, Ruirui Liu, Richard Qiu, Xiaofeng Yang   +6 more
wiley   +1 more source

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

Advanced Science, Volume 12, Issue 33, September 4, 2025.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao, Lin Zeng, Jiaren Wang, Chang Hong, Ziyong Zhang, Chengkai Wu, Hao Cui, Yan Li, Ruining Li, Shengxing Liang, Qijie Deng, Wenyuan Li, Xuejing Zou, Pengcheng Ma, Li Liu   +14 more
wiley   +1 more source