Results 191 to 200 of about 34,555 (299)

Integrative Omics Defines Metabolic Biomarkers and Genetic Regulatory Mechanisms of Mortality Risk

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
Understanding mortality mechanisms remains a fundamental challenge. Through multi‐omics analysis of a three‐generation chicken model, are identified 45,585 mQTLs and establish a 16‐metabolite predictor of mortality. An inflammation‐growth trade‐off and evolutionarily conserved pathways involving butyrate–microbiota interactions and L‐cysteine's dual ...
Peihao Liu   +10 more
wiley   +1 more source

Case report of an aggressive cardiac myxofibrosarcoma with rapid disease progression. [PDF]

open access: yesEur Heart J Case Rep
Nakamura K   +4 more
europepmc   +1 more source

Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley   +1 more source

Ultra‐Sensitive and Linear Flexible Pressure Sensors with Tri‐Scale Graded Microstructures for Advanced Health Monitoring and Robotic Perception

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
A flexible piezoresistive sensor with a 3D tri‐scale graded microstructure is proposed, overcoming the trade‐off between sensitivity and linearity. The device achieves ultra‐high sensitivity (138.6 kPa−1), a broad linear range (400 kPa, R2 = 0.99), and exceptional stability (24 000 repeated loading cycles), enabling precise detection of physiological ...
Rui Chen   +6 more
wiley   +1 more source

Primate Swallowing Is Powered by Both Rotation and Contraction of Suprahyoid Muscles

open access: yesAmerican Journal of Biological Anthropology, Volume 189, Issue 1, January 2026.
ABSTRACT Objectives Swallowing biomechanics in primates and other mammals is poorly understood, and the effect of hyoid descent on swallowing biomechanics lacks experimental interrogation. In macaques, which share similar swallowing kinematics with humans, the base of the tongue and the food bolus are hypothesized to be driven into the oropharynx by a ...
Courtney P. Orsbon   +2 more
wiley   +1 more source

Nanoplastics trigger glial–neuronal collagen signaling miscommunication to exacerbate cognitive impairment in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) is a progressive neurodegenerative disorder with limited treatments and poorly defined environmental risks. Micro‐ and nanoplastics (MNPs) are widespread pollutants linked to neurotoxicity, but their role in AD remains unclear.
Yizhou Zhong   +20 more
wiley   +1 more source

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