Results 221 to 230 of about 34,555 (299)

Collagen XV preserves heart function and protects from pathological remodelling after myocardial infarction

The FEBS Journal, Volume 293, Issue 2, Page 418-442, January 2026.
We analysed collagen XV expression in myocardial infarct samples and assessed how its deficiency affects cardiac responses, such as fibrogenesis and tissue stiffness. In mice, damage caused by myocardial infarction is exacerbated in the absence of collagen XV and leads to pathological remodelling and more severe left ventricle dysfunction (left panel ...
Sanna‐Maria Karppinen, Miki Aho, Zoltan Szabo, Johanna Magga, Laura Vainio, Erhe Gao, Paul Janmey, Lauri Eklund, Karolina Rasi, Ilkka Miinalainen, Lynn Y. Sakai, Lasse Pakanen, Heikki Huikuri, Juhani Junttila, Risto Kerkelä, Taina Pihlajaniemi   +15 more
wiley   +1 more source

High-fidelity, personalized cardiac modeling via AI-driven 3D reconstruction and embedded silicone rubber printing. [PDF]

Exp Biol Med (Maywood)
Wang X, Li Y, Liang Z, Du R, Song T.
europepmc   +1 more source

Deep Learning‐Based Prediction Model for Cardiac Resynchronization Therapy Responders Using Electrocardiogram Data

Journal of Cardiovascular Electrophysiology, Volume 37, Issue 1, Page 157-164, January 2026.
ABSTRACT Background Cardiac resynchronization therapy (CRT) is an established treatment for advanced heart failure, but approximately 30% of patients fail to respond. This study aimed to develop and evaluate deep learning models using preimplantation electrocardiogram (ECG) data to predict CRT response.
Hitoshi Mori, Yuya Fujisaki, Syunta Higuchi, Masataka Narita, Daisuke Kawano, Kazuhisa Matsumoto, Wataru Sasaki, Tsukasa Naganuma, Naomichi Tanaka, Kazuhiko Kuinose, Haruka Yamazaki, Hiroki Yamazaki, Wataru Yoshino, Toshiki Takeda, Yoshifumi Ikeda, Ritsushi Kato   +15 more
wiley   +1 more source

A Rare Case of a Decade-Long Device-Related Thrombus with a Unique "Tree-Ring" Structure. [PDF]

Anatol J Cardiol
Yang J, Bai W.
europepmc   +1 more source

Cardiac fibrosis induced by high‐fat diet in ApoE‐deficient male mice is exacerbated by genetic deletion of PACAP–PAC1 signaling

Journal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract Cardiac fibrosis is characterized by an excessive accumulation of extracellular matrix proteins and occurs in a variety of cardiac diseases, such as the highly prevalent syndrome heart failure with preserved ejection fraction (HFpEF) and other cardiac disorders.
J. M. Schubart, M. K. H. Schaefer, G. A. Bonaterra, L. Mey, H. Schwarzbach, S. Pankuweit, F. Ausbuettel, L. E. Eiden, S. Weyand, E. Weihe, R. Kinscherf, C. Waechter   +11 more
wiley   +1 more source

The Left Atrial Appendage in Sinus Rhythm and Atrial Fibrillation: From Functional Structure to Potential Thromboembolic Reservoir, Rationale for Medical or Radical Exclusion. [PDF]

J Clin Med
Zeitani J, Likaj E, Nazzaro MS, Dibra A, Sievert K, Sievert H.   +5 more
europepmc   +1 more source

Fundamentals of System Design for Cardiac Pulsed Field Ablation: Optimization of Safety, Efficacy, and Usability

Pacing and Clinical Electrophysiology, Volume 49, Issue 1, Page 5-14, January 2026.
ABSTRACT The goal of a cardiac pulsed field ablation (PFA) system is to provide safe, effective, and usable therapy for the treatment of cardiac arrhythmias. Achieving this goal is a complex exercise in system design, requiring optimization of catheter, waveform, and dosing. This optimization is often iterative, as myriad design factors are balanced to
Brendan Koop
wiley   +1 more source

ES-UNet: efficient 3D medical image segmentation with enhanced skip connections in 3D UNet. [PDF]

BMC Med Imaging
Park M, Oh S, Park J, Jeong T, Yu S.
europepmc   +1 more source

Lesion Formation in Cardiac Pulsed‐Field Ablation: Acute to Chronic Cellular Level Changes

Pacing and Clinical Electrophysiology, Volume 49, Issue 1, Page 32-42, January 2026.
ABSTRACT As pulsed‐field ablation (PFA) emerges as a promising therapy for atrial arrhythmias, an understanding of the cellular injury to cardiac tissue is critical to evaluating and interpreting results for each PFA system. This review aims to detail the mechanism of cell death for PFA, compare the cell death mechanism to thermal ablation modalities ...
Kara Garrott, Savannah Bifulco, David Ramirez, Brendan Koop   +3 more
wiley   +1 more source

Primary Intraventricular Amelanotic Melanoma: Case Report and Literature Review. [PDF]

Cureus
Mávita Corral C, Hernandez-Gonzalez F, Toache KS, Rodriguez-Florido MA, Gallego Hermosillo LA, Suarez-Ramirez A, Gonzalez-Zavala PA.   +6 more
europepmc   +1 more source