Results 231 to 240 of about 114,786 (336)

Intraoperative Clonidine in Spine Surgery: A Randomised Controlled Trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 69, Issue 6, July 2025.
ABSTRACT Patients undergoing spine surgery often experience post‐operative pain. In this context, clonidine, an alpha‐2 agonist, may be relevant due to its analgesic properties. We conducted a randomised, double‐blinded, placebo‐controlled trial to evaluate the effect of a single dose of intraoperative intravenous clonidine on post‐operative opioid ...
Stine Birkebæk   +4 more
wiley   +1 more source

G protein‐coupled receptor‐mediated autophagy in health and disease

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 14, Page 3151-3162, July 2025.
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan   +2 more
wiley   +1 more source

Retrospective evaluation of the impact of atropine administration on incidence of post‐operative colic in healthy, isoflurane‐anaesthetised horses

open access: yesEquine Veterinary Journal, Volume 57, Issue 4, Page 924-930, July 2025.
Abstract Background In anaesthetised horses, bradycardia secondary to high vagal tone can reduce cardiac output and blood pressure. The use of anticholinergics in horses is limited due to concerns about ileus and abdominal discomfort. This retrospective study sought to determine the prevalence of post‐operative abdominal discomfort in healthy horses ...
Kelley M. Varner   +4 more
wiley   +1 more source

Efficacy of Injectable Bone Fillers for Alveolar Ridge Preservation: A Histomorphometrical Analysis

open access: yesJournal of Clinical Periodontology, Volume 52, Issue 7, Page 949-959, July 2025.
ABSTRACT Aim To assess the efficacy of injectable bone fillers for alveolar ridge preservation (ARP). Materials and Methods The mandibular premolars (P2, P3, P4) were bilaterally assigned to ARP in a total of n = 9 beagle dogs. Each P was decapitated and hemisected under preservation of the mesial (i.e., devitalization and filling with calcium ...
Frank Schwarz   +5 more
wiley   +1 more source

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