Vascular remodeling in arteriovenous fistula treated with PDE5A inhibitors
Physiological Reports, Volume 13, Issue 9, May 2025.Abstract The arteriovenous fistula (AVF) is the lifeline for hemodialysis patients. However, there are currently no effective therapies promoting AVF maturation. AVF dilation by smooth muscle cell relaxation, through increased cyclic guanosine monophosphate (cGMP), is one potential mechanism to improve AVF remodeling.
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