Results 41 to 50 of about 712,622 (298)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Child–Dog Attachment, Emotion Regulation and Psychopathology: The Mediating Role of Positive and Negative Behaviours

open access: yesBehavioral Sciences, 2022
Emerging evidence suggests that pet dogs can offer features of a secure attachment which has been associated with healthy psychological development across the lifespan.
Roxanne D. Hawkins   +2 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

CLINICAL PROFILE AND MANAGEMENT OF PATIENTS WITH CARCINOMA GALL BLADDER

open access: yesBasrah Journal of Surgery
Gallbladder cancer (GBC) is an aggressive malignancy with an extremely poor prognosis. It is the most common cancer of the biliary tree. The early symptoms of gallbladder carcinoma are generally nonspecific and often mimic those of more common calculous ...
vinamra mittal   +2 more
doaj   +1 more source

Underlying Role of Rumination-Mediated Attachment Style Plays in PTSD after TIA and Stroke

open access: yesBrain Sciences, 2022
Objective: Attachment and rumination were examined as the intermediary variables on post-traumatic stress disorder and medication compliance in stroke or TIA patients.
Kaiping Zhou   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Breakup grief: The difference between initiator and non-initiator depending on coping strategies and attachment [PDF]

open access: yesZbornik Radova Filozofskog Fakulteta u Prištini, 2020
The aim of this paper is to examine the difference in the intensity of the breakup distress between the initiator and the non-initiator, as well as whether this difference is moderated by coping strategies and inner working models according to the ...
Ranđelović Kristina Ž.   +1 more
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Modulation of gregarious settlement of the stalked barnacle, Pollicipes pollicipes: a laboratory study

open access: yesScientia Marina, 2016
Although recruitment patterns of Pollicipes pollicipes (Crustacea: Scalpelliformes) in the wild have been investigated, no studies have yet focused on the factors that affect settlement. In the present paper, settlement of P.
Sofia C. Franco   +3 more
doaj   +1 more source

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