Results 121 to 130 of about 19,388,770 (317)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Finding mobility in place attachment research: lessons for managed retreat
Frontiers in ClimateClimate change will affect many global landscapes in the future, requiring millions of people to move away from areas at risk from flooding, erosion, drought and extreme temperatures.
Robin Willcocks-Musselman +5 more
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Fides et Ratio, 2018 This article is an attempt to show the life-giving meaning of touch in the attachment relationship. Touch is the most original way of communication and a transmitter of feelings between a guardian and child.
Alicja Libura-Gil
doaj
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Exploring attachment as a triadic process: The family attachment interview
Human Systems: Therapy, Culture and AttachmentsAttachment theory offers a profound conceptual shift in moving beyond individualised explanations to relational ones. With its battery of assessments based on understanding parent-child interaction and relational narratives, the field has built a considerable evidence base for understanding problems as residing between people rather than in people.
Rudi Dallos, Ben Grey, Rebecca Stancer
openaire +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Preterm Birth’s Effects on Attachment
Cam & Sakura Medical JournalThe attachment established between the caregiver and the infant is a fundamental factor affecting mental health, starting from the prenatal period and developing during infancy.
Elif Yerlikaya Oral, Gül Karaçetin
doaj +1 more source