Results 51 to 60 of about 1,069,110 (304)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hamas, from the Muslim Brotherhood, to the thirst to kill and dominate, and up to the atrocities of the October 7

open access: yesPerspective Politice
In this paper, I analyze the links between the ideological background from which Hamas draws its roots, part of the history preceding its conflict with Israel, the transformation that Hamas went through until its establish-ment as a terrorist ...
Mircea-George Bucurescu
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Dead wood retention and the risk of bark beetle attack [PDF]

open access: yes, 2002
Wind-felled Norway spruce trees left for conservation purposes and spruce stems stored as forest fuel may be colonised by the bark beetles Ips typographus and Pityogenes chalcographus (Coleoptera: Scolytidae).
Hedgren, Per Olof
core   +1 more source

METHODOLOGICAL PROBLEMS AND WAYS OF CREATION OF THE AIRCRAFT EQUIPMENT TEST AUTOMATED MANAGEMENT SYSTEM

open access: yesНаучный вестник МГТУ ГА, 2017
The development of new and modernization of existing aviation equipment specimens of different classes are accompanied and completed by the complex process of ground and flight tests. This phase of aviation equipment life cycle is implemented by means of
V. M. Vetoshkin   +2 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Valid attacks in argumentation frameworks with recursive attacks

open access: yesAnnals of Mathematics and Artificial Intelligence, 2020
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Cayrol, Claudette   +3 more
openaire   +4 more sources

Attack-like camera angle.

open access: yes, 2023
One of the hallmarks of the collective movement of large schools of pelagic fish are waves of shimmering flashes that propagate across the school, usually following an attack by a predator.
Assaf Pertzelan (16632091)   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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