Results 91 to 100 of about 574,096 (277)

Construction of advanced persistent threat attack detection model based on provenance graph and attention mechanism

Tongxin xuebao
In response to the difficulty of existing attack detection methods in dealing with advanced persistent threat (APT) with longer durations, complex and covert attack methods, a model for APT attack detection based on attention mechanisms and provenance ...
Yuancheng LI, Hao LUO, Xinyu WANG, Jiexuan YUAN   +3 more
doaj   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Multi-type low-rate DDoS attack detection method based on hybrid deep learning

网络与信息安全学报, 2022
Low-Rate distributed denial of service (DDoS) attack attacks the vulnerabilities in the adaptive mechanism of network protocols, posing a huge threat to the quality of network services.Low-Rate DDoS attack was characterized by high secrecy, low attack ...
Lijuan LI, Man LI, Hongjun BI, Huachun ZHOU   +3 more
doaj  

Unorganized Malicious Attacks Detection

CoRR, 2016
Recommender system has attracted much attention during the past decade. Many attack detection algorithms have been developed for better recommendations, mostly focusing on shilling attacks, where an attack organizer produces a large number of user profiles by the same strategy to promote or demote an item.
Ming Pang, Wei Gao 0008, Min Tao, Zhi-Hua Zhou   +3 more
openaire   +3 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

RLXSS: Optimizing XSS Detection Model to Defend Against Adversarial Attacks Based on Reinforcement Learning

Future Internet, 2019
With the development of artificial intelligence, machine learning algorithms and deep learning algorithms are widely applied to attack detection models. Adversarial attacks against artificial intelligence models become inevitable problems when there is a
Yong Fang, Cheng Huang, Yijia Xu, Yang Li   +3 more
doaj   +1 more source

Attack Detection in Wireless Localization

IEEE INFOCOM 2007 - 26th IEEE International Conference on Computer Communications, 2007
Accurately positioning nodes in wireless and sensor networks is important because the location of sensors is a critical input to many higher-level networking tasks. However, the localization infrastructure can be subjected to non-cryptographic attacks, such as signal attenuation and amplification, that cannot be addressed by traditional security ...
Yingying Chen 0001, Wade Trappe, Richard P. Martin   +2 more
openaire   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source