Results 71 to 80 of about 3,338,637 (201)

Construction of advanced persistent threat attack detection model based on provenance graph and attention mechanism

open access: yesTongxin xuebao
In response to the difficulty of existing attack detection methods in dealing with advanced persistent threat (APT) with longer durations, complex and covert attack methods, a model for APT attack detection based on attention mechanisms and provenance ...
Yuancheng LI   +3 more
doaj   +2 more sources

Research on wormhole attacks in wireless mesh networks

open access: yesTongxin xuebao, 2011
In order to detect the wormhole attacks effectively in wireless mesh network,a wormhole attack model ac-cording to the MR-LQSR(multi-radio link-quality source routing) protocol proposed by Microsoft was presented.Then,the characteristics of wireless mesh
FU Ying-fang1   +3 more
doaj   +2 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Detection Techniques for Sybil Attack in MANETs [PDF]

open access: yes, 2015
For detection of a Sybil attack, a traditional method defenses against attacks rely on trusted identities provided by a certification authority, but requiring users to present trusted identities run counter to the open membership that underlies the ...
Shamikh Faraz
core   +1 more source

DDoS attack detection method using cluster analysis

open access: yes, 2008
Distributed Denial of Service (DDoS) attacks generate enormous packets by a large number of agents and can easily exhaust the computing and communication resources of a victim within a short period of time.
Kwon, Ki Hoon   +4 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Recent Advances in Cardiac Troponin I Based Sensors for Detection of Human Heart Attack

open access: yes, 2016
Cardiovascular disease (CVD) is considered as a major life threat in human globally, and with time more sophisticated technique for estimating and therapeutics is still desirable.
Bhatnagar, Deepika   +4 more
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

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