Results 41 to 50 of about 3,338,637 (201)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
An attack detection method based on deep learning for internet of things
Scientific ReportsWith the rapid development of Internet of Things (IoT) technology, the number of network attack methods it faces is also increasing, and the malicious network traffic generated is growing exponentially.
Yihan Yu +4 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Impersonation Attack Detection in IoT Networks
, 2022 Impersonation Attack Detection in IoT ...
Keshav Sood (13078764) +4 more
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Attack simulation and signature extraction of low-rate DDoS
Tongxin xuebao, 2008 LDDoS （low-rate distributed denial-of-service） was a new type of DDoS attack. It had small traffic and cov- ered by normal network traffic. LDDoS attack was so stealthy that the detection and defense approaches of traditional DDoS could not be effective.
WU Zhi-jun, ZHANG Dong
doaj +2 more sources
An Shilling Attack Detection Algorithm Based on Item Popularity and Novelty Degree Features
工程科学与技术, 2017 :The existing supervised detection algorithms have low precision when they detect shilling attacks.To address this problem,a shilling attack detection algorithm based on the features of popularity and novelty degree was proposed.Firstly,according to the ...
于洪涛, 周倩楠, 张付志
doaj
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source