Results 91 to 100 of about 3,573,456 (297)

Research on wormhole attacks in wireless mesh networks

Tongxin xuebao, 2011
In order to detect the wormhole attacks effectively in wireless mesh network,a wormhole attack model ac-cording to the MR-LQSR（multi-radio link-quality source routing） protocol proposed by Microsoft was presented.Then,the characteristics of wireless mesh
FU Ying-fang1, ZHANG Xing1, ZHANG Ting1, LUAN Liang-yu3   +3 more
doaj   +2 more sources

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Construction of advanced persistent threat attack detection model based on provenance graph and attention mechanism

Tongxin xuebao
In response to the difficulty of existing attack detection methods in dealing with advanced persistent threat (APT) with longer durations, complex and covert attack methods, a model for APT attack detection based on attention mechanisms and provenance ...
Yuancheng LI, Hao LUO, Xinyu WANG, Jiexuan YUAN   +3 more
doaj   +2 more sources

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Recent Advances in Cardiac Troponin I Based Sensors for Detection of Human Heart Attack

, 2016
Cardiovascular disease (CVD) is considered as a major life threat in human globally, and with time more sophisticated technique for estimating and therapeutics is still desirable.
Bhatnagar, Deepika, Singh, M.P., Kumar, Ashok, Kaur, Inderpreet, Patil, S.   +4 more
core  

DDoS attack detection method using cluster analysis

, 2008
Distributed Denial of Service (DDoS) attacks generate enormous packets by a large number of agents and can easily exhaust the computing and communication resources of a victim within a short period of time.
Kwon, Ki Hoon, Han, Younggoo, Kim, Sehun, Lee, Keunsoo, Kim, Juhyun   +4 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Attack detection model for BCoT based on contrastive variational autoencoder and metric learning

Journal of Cloud Computing: Advances, Systems and Applications
With development of blockchain technology, clouding computing and Internet of Things (IoT), blockchain and cloud of things (BCoT) has become development tendency. But the security has become the most development hinder of BCoT.
Chunwang Wu, Xiaolei Liu, Kangyi Ding, Bangzhou Xin, Jiazhong Lu, Jiayong Liu, Cheng Huang   +6 more
doaj   +1 more source