ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine +40 more
wiley +1 more source
TrustFed-RHIO: an optimization-driven differential privacy federated learning framework for secure and explainable IIoT attack detection. [PDF]
Joseph L, Prabha B, Sambath M.
europepmc +1 more source
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin +8 more
wiley +1 more source
A hybrid XGBoost-SVM ensemble framework for robust cyber-attack detection in the internet of medical things (IoMT). [PDF]
Abdelhaq M +5 more
europepmc +1 more source
Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse +13 more
wiley +1 more source
Retraction Note: Strengthening network DDOS attack detection in heterogeneous IoT environment with federated XAI learning approach. [PDF]
Almadhor A +4 more
europepmc +1 more source
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
Advanced security framework for 5G-SDN attack detection and mitigation using Affinity Cohesive Clustering and Improved Chaotic Walrus-Optimized Convolutional LSTM with Deep Dual Info-Varcoder. [PDF]
R S, Rajkumar S.
europepmc +1 more source
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab +19 more
wiley +1 more source
Transparent and trustworthy CyberSecurity: an XAI-integrated big data framework for phishing attack detection. [PDF]
Nauman M +4 more
europepmc +1 more source

