Results 131 to 140 of about 42,587 (259)

A Phase 1 Study of Convection‐Enhanced Delivery of Intraputaminal AAV2‐GDNF in Advanced Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder. Neurotrophic therapeutic approaches have been limited in part by incomplete delivery to the putamen. We developed image‐guided convection‐enhanced delivery with real‐time monitoring to improve intraputaminal distribution of neurotrophic gene therapy. Objectives To
John D. Heiss, Debra J. Ehrlich, Codrin Lungu, Joseph Y. Choi, Gretchen Scott, Irene Dustin, Dima A. Hammoud, Peter Herscovitch, Russell R. Lonser, Kareem A. Zaghloul, Krystof Bankiewicz   +10 more
wiley   +1 more source

The Impact of Attempted Suicide on Young Adults: Learning from the Lived Experiences of UK Students in Further and Higher Education. [PDF]

Healthcare (Basel)
Smit J, Marzano L, Colucci E.
europepmc   +1 more source

Attempted suicide in older people in New South Wales, Australia, 1870-1908. [PDF]

Hist Psychiatry, 2023
Draper B.
europepmc   +1 more source

Oral GLP‐1RA TERN‐601 for Adults With Obesity/Overweight: Placebo‐Controlled, Multiple‐Ascending‐Dose, Phase 1 and 2 Studies

Obesity, EarlyView.
ABSTRACT Objective The safety, tolerability, pharmacokinetics, and efficacy of TERN‐601, a once‐daily, oral small‐molecule glucagon‐like peptide‐1 (GLP‐1) receptor agonist, were studied in Phase 1 and 2 clinical studies. Methods The Phase 1 (28‐day) and Phase 2 (12‐week), randomized, double‐blind, placebo‐controlled, multiple‐ascending‐dose studies ...
W. Timothy Garvey, Julio Rosenstock, Harold E. Bays, Douglas Denham, Anita Kohli, Melanie Haines, Christopher Jones, Ellen Kwan, Erin Castelloe, Tonya Marmon, Emil Kuriakose, Cara Nelson   +11 more
wiley   +1 more source

Suicide attempt by a cancer caregiver: A husband who attempted suicide two months after his wife was diagnosed with advanced stomach cancer. [PDF]

Palliat Support Care
Ishida M, Ooya Y, Kawanishi C, Kashiwagi T, Onishi H.   +4 more
europepmc   +1 more source

Sources of Strength for School‐Based Suicide Prevention: Key Implementation Strategies Based on School Professional Perspectives

Psychology in the Schools, EarlyView.
ABSTRACT As concerns for rising rates of youth suicide and suicidal thoughts and behaviors continue to grow, there is a need to prioritize school‐based suicide prevention programs. Despite evidence documenting the effectiveness of school‐based prevention programs for reducing suicide‐related risk in adolescents, schools face numerous barriers to ...
Marisa E. Marraccini, Maya Gutman, Layne A. Wetherbee, Jessica R. Jacobs, Donald Christian Fisher, Dorothy L. Espelage, Sarah Haley McGlothin, Denise Yookong Williams, Paul Lanier   +8 more
wiley   +1 more source

An Analytical Cross-Sectional Study Among Adolescent Patients Who Attempted Suicide and Their Childhood Mobility. [PDF]

J Child Adolesc Psychiatr Nurs
Yang Y, Balabhadruni M, Rodriguez SR, Vuong D, Vazquez Camberos V, Morales D, Wadood H, Alvarez O.   +7 more
europepmc   +1 more source

Levels of IL-6 are Associated with Lifetime Attempted Suicide in Alcohol Use Disorder Patients. [PDF]

Neuropsychiatr Dis Treat, 2023
Bramness JG, Pandey S, Moe JS, Toft H, Lien L, Walby FA, Myhre MØ, Bolstad I.   +7 more
europepmc   +1 more source

Accidental plant poisonings in France: Lessons from a decade of national toxicovigilance

PLANTS, PEOPLE, PLANET, EarlyView.
Accidental plant poisonings reveal how modern societies are losing everyday botanical knowledge once central to food and health safety. By analyzing a decade of French toxicovigilance data, this study shows that most severe cases arise from plant misidentification or misguided self‐medication.
Gaël Le Roux, Adrien Maillot, Sylvie Michel, Jérôme Langrand, Sébastien Larréché, Christine Tournoud, David Boels, Magali Labadie, Nicolas Delcourt, Nathalie Paret, Luc de Haro, Sandra Sinno‐Tellier   +11 more
wiley   +1 more source

The exploratory relationship between spiritual health and depression, anxiety, and stress in individuals who attempted suicide in Yasuj, Southwest Iran: a cross-sectional study. [PDF]

BMC Psychiatry
Manzouri L, Karami A, Malekzadeh M, Seyed-Nezhad M, Moradi-Joo M.   +4 more
europepmc   +1 more source