Results 201 to 210 of about 2,909,735 (249)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Effects of a Virtual Reality-Based Natural Environment Intervention on Attention and Mood in Community-Dwelling Older Adults: Randomized Controlled Trial. [PDF]

JMIR Aging
Chou CC, Lin JN, Yu CP, Chen CW, Yeh AY, Lin YK.   +5 more
europepmc   +1 more source

Scientific reports multi relational dual attention graph transformer for fine grained sentiment analysis. [PDF]

Sci Rep
Anilkumar AP, Kim SK, Yoon YC.
europepmc   +1 more source

Exploring within and between associations of momentary mindfulness and emotion regulation and the moderating effects of mental health among adolescents. [PDF]

J Res Adolesc
Miller-Chagnon RL, Prince MA, Haddock SA, Zimmerman TS.   +3 more
europepmc   +1 more source

Robust salient object detection based on triple attention-guided multi-resolution fusion and feature refinement. [PDF]

PLoS One
Wei G, Zhou M, Sun J, Shi X, Yin M, Zhao X, Lin X.   +6 more
europepmc   +1 more source

MAAR-Net: Multi-scale attention-assisted residual neural network for renal microvascular structure segmentation. [PDF]

PLoS One
Wang T, Lin B, Jiang T, Wang H, Yang D, Shang F, Li L, Li Y, Zhao M, Xu Y, Yan Y.   +10 more
europepmc   +1 more source