Results 231 to 240 of about 3,113,380 (249)

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

From radiomics to transformers in pancreatic cancer detection and prognosis. [PDF]

Front Med (Lausanne)
Almufareh MF, Tehsin S, Humayun M, Kausar S, Farooq A, Aldossary H, Aljohani A.   +6 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Developing an AI-driven multimodal approach to visualising resilient team performance: joint attentional engagement with gaze and speech in simulated emergency scenarios. [PDF]

BMJ Open Qual
Miyazaki A, Coffey F, Sato H, Mackenzie AK, Nakamura K, Bise K, Saitoh T, Abe T, Fuyuno M, Timmons S, Tsuchiya K.   +10 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

It takes a village, not questionnaires, to improve children's sleep health: A commentary on community-driven sleep health

Sleep Medicine: X
Reut Gruber
doaj   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

ASSAFormer: a sensor data-based approach to human activity recognition. [PDF]

Sci Rep
Zeng J, Peng B, Chen C.
europepmc   +1 more source

Enhanced remaining useful life prediction of lithium-ion battery based on a dual attention hybrid data-driven method. [PDF]

Sci Rep
Shi Z, Ibrahim AW, Xu J, Zeng L, Farh HMH, Al-Shamma'a AA, Ameur K.   +6 more
europepmc   +1 more source

A lightweight CVTC model for accurate Alzheimer's MRI analysis and lesion annotation. [PDF]

NPJ Digit Med
Lu Y, Yu H, Li T, Meng Y, Lu J, Li P.
europepmc   +1 more source