Results 171 to 180 of about 4,580,020 (399)
Rational Design of Inner Ear Drug Delivery Systems
Advanced Science, EarlyView.Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang +5 morewiley +1 more sourceSubcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis.
Lancet psychiatry, 2017 M. Hoogman, J. Bralten, D. Hibar, M. Mennes, M. Zwiers, L. Schweren, K. V. Hulzen, S. Medland, E. Shumskaya, N. Jahanshad, P. Zeeuw, E. Székely, G. Sudre, T. Wolfers, A. Onnink, J. Dammers, J. Mostert, Y. Vives-Gilabert, G. Kohls, E. Oberwelland, J. Seitz, M. Schulte-Rüther, S. Ambrosino, A. Doyle, M. F. Høvik, Margaretha Dramsdahl, L. Tamm, T. Erp, A. Dale, A. Schork, A. Conzelmann, K. Zierhut, Ramona Baur, H. McCarthy, Yuliya Yoncheva, A. Cubillo, K. Chantiluke, M. Mehta, Y. Paloyelis, S. Hohmann, S. Baumeister, Ivanei E. Bramati, P. Mattos, F. Tovar-Moll, P. Douglas, T. Banaschewski, D. Brandeis, J. Kuntsi, P. Asherson, K. Rubia, C. Kelly, A. Martino, M. Milham, F. Castellanos, T. Frodl, M. Zentis, K. Lesch, A. Reif, P. Pauli, T. Jernigan, J. Haavik, Kerstin J. Plessen, A. Lundervold, K. Hugdahl, L. Seidman, J. Biederman, N. Rommelse, D. Heslenfeld, C. Hartman, P. Hoekstra, J. Oosterlaan, G. V. Polier, K. Konrad, Ó. Vilarroya, J. Ramos-Quiroga, J. Soliva, S. Durston, J. Buitelaar, S. Faraone, P. Shaw, P. Thompson, B. Franke, Stephen M. Smith, Thomas E. Nichols, Amy N. Taylor, H. Jones, H. Sallis, G. Smith, D. Lawlor, N. Davies, E. Stergiakouli, M. Munafo, J. Euesden, K. Tilling, S. Zammit, T. Kubota, K. Miyake, N. Hariya, K. Mochizuki, K. Rosch, D. Crocetti, Kathryn Hirabayashi, M. Denckla, S. Mostofsky, E. Mahone, S. Ducharme, Matthew D. Albaugh, Tuong-Vi Nguyen, J. Hudziak, J. M. Mateos-Pérez, A. Labbe, A. Evans, S. Karama, W. Ball, A. Byars, M. Schapiro, W. Bommer, A. Carr, A. German, S. Dunn, M. Rivkin, D. Waber, R. Mulkern, S. Vajapeyam, A. Chiverton, Peter E. Davis, J. Koo, J. Marmor, C. Mrakotsky, R. Robertson, G. McAnulty, M. Brandt, J. Fletcher, L. Kramer, G. Yang, C. McCormack, K. M. Hebert, H. Volero, K. Botteron, R. McKinstry, W. Warren, T. Nishino, C. Almli, R. Todd, J. Constantino, J. Levitt, J. Alger, J. O’Neil, A. Toga, R. Asarnow, D. Fadale, L. Heinichen, C. Ireland, Dah‐Jyuu Wang, E. Moss, R. Zimmerman, B. Bintliff, R. Bradford, J. Newman, R. Arnaoutelis, G. Pike, D. Collins, G. Leonard, T. Paus, A. Zijdenbos, Samir Das, Vladimir S Fonov, L. Fu, J. Harlap, I. Leppert, D. Milovan, D. Vins, T. Zeffiro, J. Meter, N. Lange, M. P. Froimowitz, C. Rainey, Stanley E. Henderson, J. L. Edwards, D. Dubois, Karla Smith, T. Singer, A. Wilber, C. Pierpaoli, P. Basser, L. Chang, C. Koay, L. Walker, L. Freund, J. Rumsey, L. Baskir, L. Stanford, K. Sirocco, K. Gwinn‐Hardy, G. Spinella, J. McCracken, J. O’Neill, H. Brinson, A. Banik, Deepika Kandilya, Seshadri Ramya, W. Stünkel, Y. Chong, S. T. Dheen, Yuliya S. Nikolova, A. Hariri, Wenjun Zhang, Xiuxia Qu, Biyi Chen, M. Snyder, Baiyan Li, Yuefei Tang, Hanying Chen, Wuqiang Zhu, Ni Yin, Deqiang Li, Xie Li, Y. Liu, J. Jillian, Xin-Yuan Fu, M. Rubart, Long-Sheng Song, W. Shou, Peking Union Medical, Iowa City, C. Wiers, Brock H Medsker, E. Forno, H. Simhan, C. Juan, R. Bansal, Hongtu Zhu, Ronald Whiteman, Georgette A Quackenbush, Laura Martin, K. Durkin, Jason Royal, B. Peterson, Martha O. Wang, Charlotte E. Vorwald, M. Dreher, Eric J. Mott, A. Çinar, Hamidreza Mehdizadeh, S. Somo, D. Dean, E. Brey, J. Fisher +247 moresemanticscholar +1 more sourceExome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene
Advanced Science, EarlyView.Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic Qing He, Min Yu, Yuhua Jiao, Yizhu Xu, Xuqin Liang, Wenbin Huang, Linping Xu, Yuxia Hou, Zhanping Ren, Beile Lyu, Zhenwei Qian, Pengpeng Liu, Jing Zhou, Huimei Huang, Chunyan Yin, Huaxiang Zhao, Yi Ding +16 morewiley +1 more sourceIncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation
Advanced Science, EarlyView.LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.Jiena Liu, Qing Lu, Zixuan Fan, Jiahui Lin, Nan He, Xin Zhang, Zhaoya Han, Tingting Zhu, Zhenzhen Wu, Yingying Xu, Yuming Wang +10 morewiley +1 more source