Results 151 to 160 of about 291,450 (287)

PRMT3‐Mediated H4R3me2a Promotes Primary Age‐Related Tauopathy by Driving Tau Hyperphosphorylation in Neuron

open access: yesAdvanced Science, EarlyView.
This study identifies PRMT3‐mediated H4R3me2a as a critical driver of tau hyperphosphorylation in primary age‐related tauopathy. Mechanistic insights reveal that the PRMT3/H4R3me2a/miR‐448 axis suppresses IGF1R expression via epigenetic regulation, further dysregulating the PI3K/AKT/GSK3β pathway.
Haotian Liu   +9 more
wiley   +1 more source

Quantitative and qualitative aspects of obsessive‐compulsive behaviour in children with attention‐deficit hyperactivity disorder compared with tic disorder [PDF]

open access: bronze, 2000
Gunther H. Moll   +5 more
openalex   +1 more source

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He   +11 more
wiley   +1 more source

Quantum Transport in SnTe Nanowire Devices

open access: yesAdvanced Electronic Materials, EarlyView.
A variety of quantum transport experiments are observed in SnTe nanowire devices and attributed to microscopic differences in the fabrication. Three categories can be distinguished: semiconducting behavior, partial superconductivity and Fabry‐Pérot oscillations.
Femke J. Witmans   +11 more
wiley   +1 more source

Detection and Quantification of Over‐Humidification in Polymer Electrolyte Fuel Cells: Insights into Simulation, Imaging, and Sensors

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
This review highlights advanced methods for detecting and managing over‐humidification in polymer electrolyte fuel cells (PEFCs), emphasizing innovative sensors, simulation techniques, and imaging methods. By addressing the impact of water management on fuel‐cell performance and durability, this study outlines practical and sustainable solutions for ...
Maximilian Käfer   +2 more
wiley   +1 more source

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