Results 31 to 40 of about 161,628 (254)
Attention deficit hyperactivity disorder in children
Неврология, нейропсихиатрия, психосоматика, 2014 Attention deficit hyperactivity disorder (ADHD) is a common neuropsychological disorder occurring in 5-8% of school-aged children. In case of late diagnosis and lack of correction, this condition may lead to intra-family problems and formation of ...
O.E. Zinov'eva +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Tricyclic Antidepressants and Attention Deficit Disorder
Pediatric Neurology Briefs, 1987 A review of the literature concerning imipramine and other tricyclics in the treatment of attention deficit disorder (ADD) is presented from the Dept Psychiatry, Univ. Texas Health Sci Cntr, 7703 Floyd Carl Drive, San Antonio, TX 78284.
J Gordon Millichap
doaj +1 more source
Emotion Dysregulation in Attention Deficit and Hyperactivity Disorder and its Treatment [PDF]
Psikiyatride Güncel Yaklaşımlar, 2018 Attention deficit hyperactivity disorder is a neurodevelopmental disorder that may seriously affect youth’s home, school, and social functions. Comorbidity with emotion dysregulation in attention deficit hyperactivity disorder increases the severity of ...
Yusuf Ozturk +3 more
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Sleep Disorders in Attention Deficit Disorder
Pediatric Neurology Briefs, 1999 Parental perceptions of sleep patterns in children presenting at an ADHD clinic in Washington, DC, were assessed prospectively over a 6-month period.
J Gordon Millichap
doaj +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Serotonin Levels in Attention Deficit Disorder
Pediatric Neurology Briefs, 1999 The relationship between blood serotonin, norepinephrine, dopa and lipid levels and the degree of hyperactivity, impulsiveness, inattention, and aggressiveness in 35 boys with ADHD, combined type, was studied at the Ness Ziona Mental Health Center, Nes ...
J Gordon Millichap
doaj +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Attention Deficit Disorder (ADD): Methylphenidate Treatment
Pediatric Neurology Briefs, 1991 The clinical response to three dose levels of methylphenidate (5, 10, and 15 mg BID) in 23 children with ADD+H and 17 children with ADD-H is reported from the Department of Psychiatry, University of Massachusetts Medical Center, Worcester, MA.
J Gordon Millichap
doaj +1 more source