Results 151 to 160 of about 65,698,273 (265)

Serotonin neuromicrobiology: Psychobiotic modulation of the gut–brain axis for mental health

Ibrain, EarlyView.
An overview of Psychobiotics and Tryptophan metabolism: A serotonin‐kynurenine crosstalk shaping the Gut‐Brain axis. IDO1, Indoleamine 2,3‐dioxygenase 1; 5‐HT3, 5‐hydroxytryptamine type 3; IFN‐γ, Interferon‐gamma; TNF‐α, Tumor necrosis factor‐alpha; IL‐1β, Interleukin‐1 beta; IL‐6, Interleukin 6; Trp, Tryptophan; 5‐HT, 5‐hydroxy‐tryptamine; 5‐HTP, 5 ...
Nidhi Mandloi, Aarzoo, Chakkaravarthi Saravanan, Heera Ram, Bhim Pratap Singh   +4 more
wiley   +1 more source

Maternal overweight and obesity during pregnancy and sex‐dependent dysregulation of the materno‐fetal stress axis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Maternal obesity and excess gestational weight gain (GWG) are linked to adverse perinatal outcomes, potentially via disruption of the maternal–fetal stress axis. Placental HSD11B2 protects the fetus from excess glucocorticoids and may influence fetal programming during maternal metabolic stress.
Thorsten Braun, Marie Hofmann, Rebecca Rancourt, Julia Sommer, Alexandra Kühn, Loreen Ehrlich, Thomas Ziska, Kerstin Melchior, Karen Schellong, Wolfgang Henrich, Sonja Entringer, Katherine Margaret Kennedy, Andreas Plagemann, Deborah Magdalena Sloboda   +13 more
wiley   +1 more source

GSK3β drives early diabetic tubulopathy via TFEB‐mediated mitochondrial dysfunction

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction, including mitochondrial biogenesis, mitophagy, dynamics and oxidative stress, occurs in the early stages of diabetic tubulopathy, which precede proteinuria and renal histological changes. GSK3β is a potential novel biomarker for the prediction of diabetic tubulopathy.
Lan Yao, Xianhui Liang, Bingyu Li, Bohan Chen, Xiaoyang Wang, Mei Hong, Qi Feng, Yingjin Qiao, Zhangsuo Liu, Kai Wang, Pei Wang   +10 more
wiley   +1 more source

Adolescents' Perspectives on Self‐Regulation and Need for Change in Digital Media Use: A Focus Group Study

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Research on digital media use and adolescents' development and well‐being remains inconclusive, and adolescents' own perspectives on these issues are largely unexplored. Nevertheless, concrete policy measures are being implemented to regulate adolescents' digital media use.
Luka Todorovic, Annabel Bogaerts, Helle Larsen   +2 more
wiley   +1 more source

Body, Emotions, and Hormones: A Systematic Review of Body Dissatisfaction, Emotion Regulation, and Puberty in Adolescence

Journal of Adolescence, EarlyView.
ABSTRACT Objective Body dissatisfaction often arises from a discrepancy between perceived and ideal body images, posing a risk for psychological issues like depression and eating pathologies, particularly during adolescence. Puberty's rapid physical changes may exacerbate the feeling of dissatisfaction, additionally pubertal changes also influence ...
Isabella Muscolino, Samantha Dockray, Maria Dempsey, Eleonora Tomei   +3 more
wiley   +1 more source

Mentalization and Emotion Regulation Difficulties in Adolescent Girls With Social Anxiety Disorder

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Social anxiety disorder (SAD) is a prevalent disorder that often begins during adolescence, leading to considerable challenges in social functioning and overall mental health. Previous studies have demonstrated that mentalization deficits and emotion regulation difficulties are each independently associated with social anxiety ...
Ayşe Selma Yenen Menderes, Isranur Yenen Sivri, Hande Günal Okumuş, Uğur Ufuk Işın, Makbule Esen Öksüzoğlu, Burcu Ersöz Alan   +5 more
wiley   +1 more source

Age-Related Cognitive Patterns in Children With Attention-Deficit/Hyperactivity Disorder and Typically Developing Children: A Comparative Study. [PDF]

J Korean Med Sci
Kim HJ, Kim KJ, Han DH, Kim SM, Hwang H, Hong JS.   +5 more
europepmc   +1 more source

Adolescent Withdrawn/Depressed Symptoms: A Pathway From Early Adversity to Later Marijuana Use

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Adverse childhood experiences (ACEs) are robust predictors of marijuana use, yet the developmental mechanisms remain unclear. Building on prior cross‐sectional studies using broad internalizing composites, this study prospectively distinguishes withdrawn/depressed from anxious/depressed symptoms as candidate mediators across ...
Mahsa P. Yousefkhani, Sara A. Vasilenko, Rachel A. Razza   +2 more
wiley   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto, Daniel Vitor de Souza, Gabriel Carvalhal de Aguiar, Ana Claudia Muniz Renno, Patricia Ramos Cury, Jean Nunes dos Santos, Rogerio Aparecido Dedivitis, Daniel Araki Ribeiro   +7 more
wiley   +1 more source

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado, Nicole Berton, Nicoli da Rosa Amaral, Inara Carbonera Biazus, Laíse Mattiollo, Jéssica Nardi, Karen Júlia de Souza dos Santos, Natália Freddo, Leonardo José Gil Barcellos, Luciana Grazziotin Rossato‐Grando   +9 more
wiley   +1 more source