Results 61 to 70 of about 12,268,759 (248)

Language Ideologies in a Business Institute: A Case Study of Linguistic and Socio-Cultural Realities [PDF]

open access: yes, 2015
This case study explored the English language related ideologies of different management groups and student representatives at a business school of Karachi, Pakistan.
Sikandar, Aliya; Institute of Business Management   +1 more
core   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

BIM-Based Attention Class Indicators for Network-Scale Road Safety Barrier Asset Management

open access: yesApplied Sciences
Road safety barriers represent a core component of the road with relevant consequences on effective safety for users. Maintaining these components in adequate conditions, within the quality admissibility thresholds, in compliance with all economic and ...
Gaetano Bosurgi   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Reviewing Performance or Changing Routines? An Analysis of the Experience of Participants in Performance Management Review Meetings [PDF]

open access: yes, 2010
The problem examined in this thesis falls under the broad question of the nature of effect of performance measurement and management (PMM) on organizational performance.
Pavlov, Andrey
core   +3 more sources

Innovation management from the inside: An approach from attention and everyday praxis

open access: yesIntangible Capital, 2017
Purpose: We attempt to deepen the understanding of innovation management from the attention and everyday life. Design/methodology/approach: Following a micro-sociological approach along with social constructivism, qualitative and inductive methods are ...
Fran Morente, Xavier Ferràs
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The standard for portfolio management

open access: yes, 2017
The Standard for Portfolio Management – Fourth Edition has been updated to best reflect the current state of portfolio management. It describe the principles that drive accepted good portfolio management practices in today’s organizations.
Project Management Institute   +1 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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