Results 131 to 140 of about 13,220,426 (366)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Neuronal Mechanisms of Visual Attention

Annual Review of Vision Science, 2015
Advances on several fronts have refined our understanding of the neuronal mechanisms of attention. This review focuses on recent progress in understanding visual attention through single-neuron recordings made in behaving subjects. Simultaneous recordings from populations of individual cells have shown that attention is associated with changes in the ...
openaire   +4 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Improvement strategies of athlete’s concentration level based on visual attention model

Scientific Reports
Different athletes have different requirements and coping methods for concentration. Research based on visual attention models can help identify individual differences and propose targeted improvement strategies to improve the concentration level of each
Jiabao Cui, Haiyang Zhou, Rongyang Chen, Danping Li, Weishan Mai, Weikun Peng, Qiusheng Long   +6 more
doaj   +1 more source

HDA-Net: H&E and RGB Dual Attention Network for Nuclei Instance Segmentation

IEEE Access
H&E-stained images (HSIs) are widely adopted for revealing cellular structures and capturing morphological changes in nuclear instance segmentation.
Yu-Han Im, Seo-Hyeong Park, Sang-Chul Lee   +2 more
doaj   +1 more source

Neurophysiologic mechanisms of attention: a selective review of early information processing in schizophrenics [PDF]

, 2001
D. Schwartz Barry
openalex   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

TCN-attention-HAR: human activity recognition based on attention mechanism time convolutional network

Scientific Reports
Wearable sensors are widely used in medical applications and human–computer interaction because of their portability and powerful privacy. Human activity identification based on sensor data plays a vital role in these fields.
Xiong Wei, Zifan Wang
doaj   +1 more source

Biased Competition Mechanisms for Visual Attention in a Multimodular Neurodynamical System [PDF]

, 2001
Gustavo Deco
openalex   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source