Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
NanoSSL: attention mechanism-based self-supervised learning method for protein identification using nanopores. [PDF]
Xie Y +9 more
europepmc +1 more source
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Human Motion Detection in Swimming Motion Video Based on Multiscale Separation Spatio-Temporal Attention Mechanism. [PDF]
Lu J.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Bearing fault diagnosis based on Kepler algorithm and attention mechanism. [PDF]
Guang YJ +5 more
europepmc +1 more source
The generation of IPDP micropulsations, with special attention to frequency shift mechanisms
Thomas W. Koleszar
openalex +1 more source
An automatic COVID-19 CT segmentation based on U-Net with attention mechanism [PDF]
Tongxue Zhou, Stéphane Canu, Su Ruan
openalex
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
SLiMs prediction method based on enhanced attention mechanism and feature fusion. [PDF]
Hao Y, He H.
europepmc +1 more source

