Results 71 to 80 of about 3,000,348 (321)

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Distractor suppression when attention fails: behavioral evidence for a flexible selective attention mechanism.

PLoS ONE, 2015
Despite consistent evidence showing that attention is a multifaceted mechanism that can operate at multiple levels of processing depending on the structure and demands of the task, investigations of the attentional blink phenomenon have consistently ...
James C Elliott, Barry Giesbrecht
doaj   +1 more source

BASN—Learning Steganography with a Binary Attention Mechanism

Future Internet, 2020
Secret information sharing through image carriers has aroused much research attention in recent years with images’ growing domination on the Internet and mobile applications.
Pin Wu, Xuting Chang, Yang Yang, Xiaoqiang Li   +3 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Attentional mechanisms in learned predictiveness.

Journal of Experimental Psychology: Animal Behavior Processes, 2012
Cues that reliably predict an outcome in an initial phase of training (Phase 1) are learned faster in a second phase of training (Phase 2) than cues that were unreliable in Phase 1. This result is observed despite objectively equal relationships between the cues and the outcomes in Phase 2, and consequently constitutes a nonnormative bias in learning ...
Mitchell, CJ, Griffiths, OD, Seetoo, J, Lovibond, PF, Seeto, Joyce   +4 more
openaire   +4 more sources

Mechanisms of perceptual attention in precuing of location [PDF]

Vision Research, 2000
What are the mechanisms of spatial attention underlying precue validity effects? We answer this question within the framework of a perceptual template model (PTM) [Lu & Dosher (1998). External noise distinguishes attention mechanisms. Vision Research, 38, 1183-1198; Dosher & Lu (1999). Mechanisms of perceptual learning.
Zhong-Lin Lu, Barbara Anne Dosher
openaire   +2 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Improving Whole-Heart CT Image Segmentation by Attention Mechanism

IEEE Access, 2020
Decent whole-heart segmentation from computed tomography (CT) can greatly contribute to the diagnosis and treatment of cardiovascular diseases. However, due to the difficulties such as blurred boundaries between neighbouring tissues and a large number of
Wei Wang, Chengqin Ye, Shanzhuo Zhang, Yong Xu, Kuanquan Wang   +4 more
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source