Results 71 to 80 of about 3,121,297 (329)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
An enhanced deep learning-based framework for diagnosing apple leaf diseases
Scientific ReportsTimely and correct identification of diseases in the apple leaf is also important in protecting crop production and sustaining agriculture. This paper introduces E-YOLOv8, a lightweight improved version of YOLOv8, that can be implemented in real-time and
Chhaya Gupta +7 more
doaj +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
PLoS ONE, 2015 Despite consistent evidence showing that attention is a multifaceted mechanism that can operate at multiple levels of processing depending on the structure and demands of the task, investigations of the attentional blink phenomenon have consistently ...
James C Elliott, Barry Giesbrecht
doaj +1 more source
A New Framework for Automatic Airports Extraction from SAR Images Using Multi-Level Dual Attention Mechanism [PDF]
, 2020 Lifu Chen +6 more
openalex +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Direct coupling analysis and the attention mechanism
BMC BioinformaticsProteins are involved in nearly all cellular functions, encompassing roles in transport, signaling, enzymatic activity, and more. Their functionalities crucially depend on their complex three-dimensional arrangement.
Francesco Caredda, Andrea Pagnani
doaj +1 more source
RNN-Based F0 Estimation Method with Attention Mechanism
InformationFundamental frequency estimation, also known as F0 estimation, is a crucial task in speech processing and analysis, with significant applications in areas such as speech recognition, speaker identification, and emotion detection.
Ales Jandera +2 more
doaj +1 more source
Neural Mechanisms of Strategic Adaptation in Attentional Flexibility [PDF]
, 2020 Anthony W. Sali +2 more
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source