Results 91 to 100 of about 504,050 (265)

Early Alzheimer’s risk detection via diffusion tensor imaging using a few-shot multichannel attention residual learning network

Frontiers in Artificial Intelligence
IntroductionAlzheimer’s disease (AD) is responsible for many dementia-related deaths worldwide, and Mild Cognitive Impairment (MCI) is often its earliest clinical manifestation.
Arpit Shet, Saad Sabahuddin, Priyadarshini B, Bhanu Naga Sai Siva Ram Jami, John Sahaya Rani Alex, Chih-Yang Lin, Chi-Wen Lung   +6 more
doaj   +1 more source

Sensor Transformation Attention Networks

CoRR, 2017
8 pages, 5 figures, 3 ...
Stefan Braun 0005, Daniel Neil, Enea Ceolini, Jithendar Anumula, Shih-Chii Liu   +4 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A network-based brain stimulation paradigm for alcohol use disorder with co-occurring major depressive disorder: a mini review targeting the ventral attention network

Frontiers in Neurology
Alcohol use disorder (AUD) is frequently complicated by co-occurring major depressive disorder (MDD), a comorbidity associated with greater clinical severity, elevated relapse risk, and poorer treatment outcomes than either condition alone.
Marc L. Copersino, Marc L. Copersino, Matthew S. Gage, Emma Joncas, Agustin G. Yip, Agustin G. Yip, Rujuta Ulhas Parlikar, Rujuta Ulhas Parlikar, Mark A. Halko, Mark A. Halko   +9 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Hybrid spatial and channel attention in post‐accident object detection

IET Intelligent Transport Systems
Analysing post‐accident scenes using in‐vehicle cameras is crucial for effective highway traffic control and enhancing accident response, road safety, and traffic flow.
Junyoung Kim, Soomok Lee
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The Effect of Task Cognitive Difficulty on Perceptual-Cognitive Indicators: Evidence on the Relationship Between Challenge Point Framework (CPF) and Cognitive Development in Table Tennis Beginners

Journal of Multidisciplinary Healthcare
Mahya Mohamad Taghi,1 Mahin Aghdaei,1 Alireza Farsi,1 Georgian Badicu,2 Matheus Santos de Sousa Fernandes,3 Fatma Hilal Yagin,4 Luca Paolo Ardigò5 1Faculty of Sports and Health Sciences, Shahid Beheshti University, Tehran, Iran; 2Department of Physical ...
Taghi MM, Aghdaei M, Farsi A, Badicu G, de Sousa Fernandes MS, Yagin FH, Ardigò LP   +6 more
doaj  

Does this smell the same? Learning representations of olfactory mixtures using inductive biases

Machine Learning: Science and Technology
Olfaction—how molecules are perceived as odors to humans—is a relatively less understood sensory system compared to vision or hearing. Recently, the principal odor map (POM) was introduced to digitize the olfactory properties of single compounds. However,
Gary Tom, Cher Tian Ser, Ella M Rajaonson, Stanley Lo, Hyun Suk Park, Brian K Lee, Benjamin Sanchez-Lengeling   +6 more
doaj   +1 more source