Results 51 to 60 of about 26,311 (266)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Frontiers in Psychology, 2023 Online learning during the COVID-19 pandemic has affected student academic performance as well as mental, physical, and social wellbeing. During a lockdown at the University of Toronto in Canada (September 2020–April 2021), my students expressed an ...
Nicole Spiegelaar
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Behavioral Sciences, 2014 Physical settings can play a role in coping with stress; in particular experimental research has found strong evidence between exposure to natural environments and recovery from physiological stress and mental fatigue, giving support to both Stress ...
Rita Berto
doaj +1 more source
Wellbeing, Space and Society, 2022 Heritage sites are complex environments that cannot be easily be located within a nature – built space dichotomy. Although a small but growing body of evidence supports the potential of visits to heritage sites in generating wellbeing benefits, there is ...
Eirini Gallou +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Psychology Research and Behavior Management, 2023 Slamet Wardoyo,1 Alkausyari Aziz,2 Taufik Anwar3 1Department of Environmental Health, Poltekkes Kemenkes Surabaya, Surabaya, Indonesia; 2Department of Nutrition, Poltekkes Kemenkes Riau, Pekanbaru, Indonesia; 3Department of Environmental Health ...
Wardoyo S, Aziz A, Anwar T
doaj
Evaluating Visual and Auditory Contributions to the Cognitive Restoration Effect
Frontiers in Psychology, 2014 It has been suggested that certain real-world environments can have a restorative effect on an individual, as expressed in changes in cognitive performance and mood. Much of this research builds on Attention Restoration Theory (ART), which suggests that
Adam G. Emfield, Mark B. Neider
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source