Results 41 to 50 of about 902,502 (236)

Rain Attenuation Correction of Reflectivity for X-Band Dual-Polarization Radar

Atmosphere, 2016
In order to improve the performance of X-band dual-polarization radars, it is necessary to conduct attenuation correction before using the X-band radar data.
Liang Feng, Hui Xiao, Guang Wen, Zongfei Li, Yue Sun, Qi Tang, Yanan Liu   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Attenuation Correction of X-Band Radar Reflectivity Using Adjacent Multiple Microwave Links

Remote Sensing, 2020
Rain attenuation can hinder the implementation of quantitative precipitation estimations using X-band weather radar. Numerous studies have been conducted on correcting the attenuation of radar reflectivity by utilizing a dual-polarimetric radar and an ...
Min-Seong Kim, Byung Hyuk Kwon
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Comparison of Methods of µ-Map Generation: MR-Based Method in PET/MR Imaging Versus Pseudo-CT Method in Radiotherapy Dose Planning [PDF]

Iranian Journal of Medical Physics
Introduction: Attenuation correction is essential for accurate PET imaging and radiotherapy (RT) dose planning. However, PET/MR systems face a significant challenge due to the lack of direct attenuation data from MR images, unlike PET/CT where CT ...
Isaac Kwesi Acquah, Stephen Inkoom, Francis Hasford   +2 more
doaj   +1 more source

Attenuation correction in single-photon emission computed tomography for NURBS-based cardiac-torso phantom using dual-energy acquisition

World Journal of Nuclear Medicine, 2020
Single photon emission tomography is widely used to detect photons emitted from the patient. Some of these emitted photons suffer from scattering and absorption because of the attenuation occurred through their path in patient's body.
Hossein Rajabi, Hadi Ahangari, Iraj Mohammadi, Alireza Mohammadkarim, Mohammad Tajik-Mansoury   +4 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Comparison of Reflectivity Factor of Dual Polarization Radar and Dual-frequency Precipitation Radar

应用气象学报, 2020
To find the root cause of the difference between spaceborne radar and ground-based radar data, their similarities and differences are quantitatively analyzed using GPM (Global Precipitation Measurement Mission) DPR (dual-frequency precipitation radar ...
Jiang Yinfeng, Kou Leilei, Chen Aijun, Wang Zhenhui, Chu Zhigang, Hu Hanfeng   +5 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source