Results 181 to 190 of about 91,672,938 (318)

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

open access: yesAdvanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu   +10 more
wiley   +1 more source

Dental Practitioners' Attitudes, Subjective Norms and Intentions to Practice Atraumatic Restorative Treatment (ART) in Tanzania. [PDF]

open access: yes
The aim of this study was to describe the attitude and subjective norm of dental practitioners towards practicing the atraumatic restorative treatment (ART) in Tanzania.
Kikwilu, Emil N   +3 more
core  

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

open access: yesAdvanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding   +7 more
wiley   +1 more source

Using digital solutions to protect people from user charges for health care: lessons from Estonia

open access: yes
iv, 12 p.The Estonian health system aims to protect people from user charges (co-payments) for outpatient prescribed medicines by reducing them for people who spend more than a certain amount a year.
World Health Organization. Regional Office for Europe
core  

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

open access: yesAdvanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya   +10 more
wiley   +1 more source

Protocol for a health technology assessment of extending BowelScreen to those aged 50 to 54 years

open access: yes
Following a request from the National Screening Advisory Committee (NSAC), HIQA has commenced work on a health technology assessment (HTA) of extending Ireland’s national colorectal cancer screening programme, BowelScreen, to those aged 50 to 54 years ...
Health Information and Quality Authority (HIQA)
core  

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

open access: yesAdvanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen   +10 more
wiley   +1 more source

Using income-based caps to protect people from user charges for health care: lessons from Austria, Belgium, Germany and Spain

open access: yes
iv, 19 p.A small number of countries in Europe protect people from user charges for health care by setting a limit – a cap – on co-payments. Some of these countries go a step further and link the cap to income, so that it gives greater protection to ...
World Health Organization. Regional Office for Europe
core  

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