Results 91 to 100 of about 361,806 (283)
Safety and Health at Work, 2011 Objectives: Ischemic heart disease (IHD) is a major cause of death in Korea and known to result from several occupational factors. This study attempted to estimate the current magnitude of IHD mortality due to occupational factors in Korea.
Jaehyeok Ha +3 more
doaj +1 more source
Estimating the healthcare cost of overweight and obesity in South Africa
Global Health Action, 2022 Background Overweight and obesity are major risk factors for noncommunicable diseases. This presents a major burden to health systems and to society in South Africa. Collectively, these conditions are overwhelming public healthcare.
Micheal Kofi Boachie +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Bounds on Dark Matter from the ``Atmospheric Neutrino Anomaly'' [PDF]
, 1997 Bounds are derived on the cross section, flux and energy density of new particles that may be responsible for the atmospheric neutrino anomaly. $4.6 \times 10^{-45} cm^2 < \sigma
Ch. Berger +14 more
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Cancers in Australia in 2010 attributable to the consumption of alcohol
Australian and New Zealand Journal of Public Health, 2015 Objective: To estimate the proportion and numbers of cancers occurring in Australia in 2010 that are attributable to alcohol consumption. Methods: We estimated the population attributable fraction (PAF) of cancers causally associated with alcohol ...
Nirmala Pandeya +5 more
doaj +1 more source
Changes in the structure and functionof the North Sea fish foodweb, 1973-2000, and the impacts of fishing and climate [PDF]
, 2005 North Sea environmental and biological data were analysed to examine 30-year changes in production and consumption in the fish food web. The analysis revealed that the demand for secondary production placed on the ecosystem by fish declined from ...
Beare +47 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Indoor particulate matter in developing countries: a case study in Pakistan and potential intervention strategies [PDF]
, 2013 Around three billion people, largely in low and middle income countries, rely on biomass fuels for their household energy needs. The combustion of these fuels generates a range of hazardous indoor air pollutants and is an important cause of morbidity and
Ian Colbeck +4 more
core +1 more source