Results 121 to 130 of about 361,806 (283)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

SAS Macros for Calculation of Population Attributable Fraction in a Cohort Study Design [PDF]

The population attributable fraction (PAF) is a useful measure for quantifying the impact of exposure to certain risk factors on a particular outcome at the population level.
Esa Virtala, Hannu Oja, Maarit A. Laaksonen, Paul Knekt, Tommi Härkänen   +4 more
core   +1 more source

The GALEX Arecibo SDSS survey: III. Evidence for the Inside-Out Formation of Galactic Disks

, 2010
We analyze a sample of galaxies with stellar masses greater than $10^{10} M_{\odot}$ and with redshifts in the range $0 ...
Azzollini, Barbara Catinella, Barnes, Blanton, Boissier, Bournard, Bruzual, Calzetti, Catinella, Chabrier, Chiappini, Conroy, Cresci, David Schiminovich, De Jong, Dutton, Fraternali, Fukugita, Gallazzi, Gil de Paz, Giovanelli, Guinevere Kauffmann, Guo, Jing Wang, Kannappan, Kauffmann, Kauffmann, Kauffmann, Kennicutt, Kron, Larson, Lotz, Martha P. Haynes, Martin, Martin, Moran, Muñoz-Mateos, Pohlen, Reichard, Riccardo Giovanelli, Roberts, Robertson, Roderik Overzier, Salim, Sancisi, Sean M. Moran, Shull, Sommer-Larsen, Tegmark, Timothy M. Heckman, Tuffs, van den Bosch, Wang, Xu Kong, Yip, York, Zaritsky, Zhang   +57 more
core   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

The 2-phase case–control design: an efficient way to use expert-time

Scandinavian Journal of Work, Environment & Health, 2016
OBJECTIVES: The objective of this paper is to show the benefits of using a 2-phase case–control (2PCC) design in identifying dose–response relationships between cumulative occupational exposure as assessed by experts and lung cancer incidence in an ...
Pascal Wild, Walter Schill, Eve Bourgkard, Karsten Drescher, Maria Gonzalez, Christophe Paris   +5 more
doaj   +1 more source

[Population attributable fraction: estimation and interpretation].

Gaceta sanitaria, 2015
The goal of this paper is to revise the concept, estimation methods, and interpretations of the population attributable fraction. From the usual formula of the population attributable fraction: (Ip ­ I₀) / Ip, where Ip is the cumulative incidence in the overall population, and I₀ is the cumulative incidence in the non-exposed group, other formulae are ...
J, Llorca, C, Fariñas-Álvareza, M, Delgado-Rodrígueza   +2 more
openaire   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source