Results 61 to 70 of about 614,208 (301)

obophenotype/bio-attribute-ontology: 2023-08-24 release

, 2023
What's Changed Added new OBA protein terms + refreshed imports by @ar-ibrahim in https://github.com/obophenotype/bio-attribute-ontology/pull/264 Update SSSOM mapping files by @rays22 in https://github.com/obophenotype/bio-attribute-ontology/pull/208 ...
Arwa Ibrahim, Chris Mungall, Meghan Balk, uberon, Daniel-Olson, David Osumi-Sutherland, Jim Balhoff, Nicole Vasilevsky, Nico Matentzoglu, Dan Keith, Vinícius de Souza, Melissa Haendel, Robyn L Ball, PhD, Ray Stefancsik, kallia-p, James McLaughlin, Charles Tapley Hoyt, paolaroncaglia, diatomsRcool   +18 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Attribute-Aware Recommender System Based on Collaborative Filtering: Survey and Classification

Frontiers in Big Data, 2020
Attribute-aware CF models aim at rating prediction given not only the historical rating given by users to items but also the information associated with users (e.g., age), items (e.g., price), and ratings (e.g., rating time).
Wen-Hao Chen, Chin-Chi Hsu, Yi-An Lai, Vincent Liu, Mi-Yen Yeh, Shou-De Lin   +5 more
doaj   +1 more source

Attributions of consciousness [PDF]

WIREs Cognitive Science, 2014
Many philosophers and brain scientists hold that explaining consciousness is one of the major outstanding problems facing modern science today. One type of consciousness in particular—phenomenal consciousness—is thought to be especially problematic. The reasons given for believing that this phenomenon exists in the first place, however, often hinge on ...
openaire   +2 more sources

obophenotype/bio-attribute-ontology: 2022-05-06 Release

, 2022
What's Changed Add disease_onset.tsv by @rays22 in https://github.com/obophenotype/bio-attribute-ontology/pull/62 Fixing the OBA edit file by @matentzn in https://github.com/obophenotype/bio-attribute-ontology/pull/66 Update ODK to 1.3.0 by @matentzn in
Chris Mungall, uberon, Meghan Balk, Jim Balhoff, Nicole Vasilevsky, Nico Matentzoglu, Dan Keith, Melissa Haendel, Ray Stefancsik, kallia-p, Charles Tapley Hoyt, paolaroncaglia, diatomsRcool   +12 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Attribute-based signature with message recovery

, 2014
We present a new notion called the attribute-based signa- ture with message recovery. Compared with the existing attribute-based signature schemes, an attribute-based signature with message recovery scheme does not require transmission of the original ...
Kefeng Wang (20117454), Yi Mu (20120565), Fuchun Guo (19583764)   +2 more
core   +1 more source

Narratives of Applying the Term Physician to Allah (Exalted be He) - Compilation and Study

Journal of Umm Al-Qura University for Shari'ah Sciences and Islamic Studies
A compilation and study of the narratives in the collections of Prophetic Sunnah that mention the use of the term "Physician" (Altabeeb) in reference to Allah, Exalted be He.
Haya salman Alsabah
doaj   +1 more source