Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Parents' preference for the inclusion of pediatric vaccines in the Chinese National Immunization Program: A discrete choice experiment. [PDF]
Wang X +7 more
europepmc +1 more source
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Assessing the effectiveness of ontology-grounded AI term extraction using OntoGPT for environmental evidence synthesis. [PDF]
Hodgson RY +8 more
europepmc +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Contextual classification of network traffic through rough set theory and convolutional neural networks. [PDF]
Priyanka D, Sundara Krishna YK.
europepmc +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Machine learning based variance estimation under two phase sampling using health and education sector data. [PDF]
Al-Marzouki S +5 more
europepmc +1 more source
Attribute based access control of geographic spatial data sharing using blockchain and smart contracts. [PDF]
Li S, Liu W, Wu Y, Wu X, Li L.
europepmc +1 more source
A new multilayer tree structure belief rule base-based prediction method for key indicators of flotation process. [PDF]
Dong H, Gong A, He W.
europepmc +1 more source

