Results 81 to 90 of about 507,975 (268)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The concept of Smart City aims to provide its citizens with infrastructure systems that make cities safer and more livable. One of the methods for doing so is collecting data from the crowd itself—termed crowdsourcing—and incorporating their ideas to ...
Parul Srivastava, Ali Mostafavi
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This paper presents a comparative study of the measurement features used as inputs of a fault locator based on Support Vector Machines, which is aimed to analyze single-phase faults.
Ever Correa-Tapasco +2 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Building projects as sub-sect of construction projects are complex and different in design and performance attributes. The prominent classes of building projects are high-rise residential buildings, hospitals, hotels, general offices, retail buildings ...
Jagadeesh Babu Ramanathan +1 more
doaj +1 more source
This paper investigates the concept of information. It follows different approaches for defining information before discussing a knowledge-in-action view on information as part of sociomaterial practices. Drawing from Stamper’s (1991) extended semiological framework the paper proposes its reinterpretation to study information as a sociomaterial ...
Boell, Sebastian K +1 more
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
In this paper it is argued that proper names, like definite descriptions, have attributive as well as referential uses. The reasons given for countenancing attributive definite descriptions are shown to apply, mutatis mutandis, to the case of names. The advantages of recognizing attributive employments of names are at least twofold: On the one hand, it
openaire +3 more sources

