Results 91 to 100 of about 170,056 (298)
, 1998 Although urban planning has used computer models and information systems sincethe 1950s and architectural practice has recently restructured to the use of computeraideddesign (CAD) and computer drafting software, urban design has hardly beentouched by ...
Batty, M +3 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
XML document design via GN-DTD [PDF]
, 2010 Designing a well-structured XML document is important for the sake of readability and maintainability. More importantly, this will avoid data redundancies and update anomalies when maintaining a large quantity of XML based documents.
Wang, Bing, Zainol, Zurinahni
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
A reference material for dynamic displacement calibration
EPJ Web of Conferences, 2010 Calibration of displacement and strain measurement systems is an essential step in providing traceability and confidence in stress and strain distributions obtained from experiment and used to validate simulations employed in engineering design ...
Whelan M. +3 more
doaj +1 more source
Facilitating the take-up of new HCI practices: a ‘diffusion of innovations’ perspective [PDF]
, 2013 The workshop Made for Sharing: HCI Stories of Transfer, Triumph & Tragedy focuses on collecting cases in which practitioners have used their HCI methods in new contexts.
Cockton, Gilbert, Vermeeren, Arnold
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
What visual literacy is not! [PDF]
, 2007 This paper intends to help design educators reach a more informed understanding of visual literacy by stating what we already know it is not, in order to promote discussion on how it can be fostered. This paper is based on Jefferies’ PhD research from an
Jefferies, Emma, Steane, Jamie
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Frontiers in Psychology, 2015 It is well-established that the experience of nature produces an array of positive benefits to mental wellbeing. Much less is known about the specific attributes of green space which produce these effects.
MaryCarol R. Hunter, Ali eAskarinejad
doaj +1 more source