Results 61 to 70 of about 170,056 (298)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Review of research in feature-based design [PDF]
, 1993 Research in feature-based design is reviewed. Feature-based design is regarded as a key factor towards CAD/CAPP integration from a process planning point of view.
Houten, F.J.A.M. van +2 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The designer's self identity - myths of creativity and the management of teams [PDF]
, 2003 This paper describes recent research conducted at Sheffield Hallam University in which practicing designers reported on their experiences of working in a cross functional team.
Fisher, T
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Customer Preference-Based Information Retrieval to Build Module Concepts
Advances in Mechanical Engineering, 2013 Preference is viewed as an outer feeling of a product, also as a reflection of human's inner thought. It dominates the designers' decisions and affects our purchase intention.
Dongxing Cao, Mandun Zhang, Zhanjun Li
doaj +1 more source
Architectures for Financial Consolidation: A Comparative Study [PDF]
, 1987 Although financial consolidation systems may share such similar components as algorithms and data structures, many systems designers are unfamiliar with the corresponding attributes of different consolidation architectures.
Sasso, William C.
core
Understanding concurrent earcons: applying auditory scene analysis principles to concurrent earcon recognition [PDF]
, 2004 Two investigations into the identification of concurrently presented, structured sounds, called earcons were carried out. One of the experiments investigated how varying the number of concurrently presented earcons affected their identification.
Blattner M. M. +25 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2019 The study proposes a methodology for extracting and applying expectation effect in multisensory user-product interaction to balance the design attributes that satisfy must-be and attractive qualities in the Kano model.
Hideyoshi YANAGISAWA, Chihiro MIYAZAKI
doaj +1 more source