Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Does Intent Regarding Abusive Supervision Really Matter? The Moderating Effect of Performance-Promotion and Injury-Initiation Attributions Between Abusive Supervision and Emotional Exhaustion. [PDF]
Behav Sci (Basel)Liu T, Kilroy S, Zhang Y.
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Signal or noise? Evaluating commonly used attribution methods for explaining deep neural networks in electrocardiogram classification. [PDF]
Eur Heart J Digit HealthArends BKO +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Auditing shortcut learning and misclassification in artificial intelligence-based breast cancer genomic subtyping. [PDF]
JAMIA OpenBorges J.
europepmc +1 more source
Multiply-Robust Causal Change Attribution [PDF]
Victor Quintas-Martinez +5 more
openalex +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
The impact of negative life events on aggressive behavior in college students: the mediating role of anger rumination and hostile attribution bias. [PDF]
Front PsycholYuan H, Wang B.
europepmc +1 more source