Results 81 to 90 of about 50,845 (249)
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
International Journal of Communication, 2019 To elucidate the Chinese public’s awareness of cancer and its possible prevention, we investigated cancer-prevention messages presented on Weibo, a Twitter-like Chinese social media platform, with reference to the extended parallel process model (EPPM ...
Jingyuan Shi +3 more
doaj
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Using attribution theory to explore the reasons adults with hearing loss do not use their hearing aids. [PDF]
PLoS One, 2020 Ritter CR, Barker BA, Scharp KM.
europepmc +1 more source
Who Is to Blame? How Fulfillment and Integrity Harms Relate to Trust in Sellers and Platforms
Journal of Theoretical and Applied Electronic Commerce ResearchThis study examines how different types of experienced harm influence trust in sellers and platforms in secondhand, platform-mediated markets. Drawing on attribution theory, we distinguish between fulfillment harm and integrity harm and investigate how ...
Na-Eun Cho
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Acta PsychologicaSocial exclusion is a common yet understudied phenomenon from the observer's perspective. This study examines how witnessing exclusion affects individuals' willingness to self-disclose and explores the mediating role of interpersonal trust and the ...
Zhiyu Ji +4 more
doaj +1 more source