Results 91 to 100 of about 46,848 (253)
Pharmaceuticals, 2010 Antidepressant therapies, such as selective serotonin reuptake inhibitors (SSRIs), are current first-line treatments for Major Depressive Disorder. However, over 50% of treated patients show an inadequate response to initial antidepressant therapy.
Allan H. Young +2 more
doaj +1 more source
An in vivo biosensor for neurotransmitter release and in situ receptor activity. [PDF]
, 2010 Tools from molecular biology, combined with in vivo optical imaging techniques, provide new mechanisms for noninvasively observing brain processes. Current approaches primarily probe cell-based variables, such as cytosolic calcium or membrane potential ...
Griesbeck, Oliver +6 more
core +2 more sources
Movement Disorders Clinical Practice, EarlyView.Abstract Background As Parkinson's disease (PD) progresses, motor fluctuations become increasingly difficult to manage with oral medications. Foslevodopa/foscarbidopa (LDp/CDp), delivered as a continuous 24‐h/day subcutaneous infusion, offers continuous levodopa delivery and stable plasma levodopa levels that reduce motor fluctuations. LDp/CDp has been
K. Ray Chaudhuri +20 more
wiley +1 more source
Voice and Speech in Atypical Parkinsonian Disorders
Movement Disorders Clinical Practice, EarlyView.Background Motor speech disorders are early, common, and functionally limiting features of atypical parkinsonian disorders (APDs) such as progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy (MSA). These impairments are underrecognized and undertreated in neurology clinics.
Federico Rodriguez‐Porcel +48 more
wiley +1 more source
Psychiatry and Behavioral Sciences, 2014 Objective: Bipolar disorder (BD) is a chronic psychiatric disorder which shows difficulties in the process of diagnosis and treatment. One of the biggest problems in BD maintenance therapy is to ensure medication compliance.
Gokay Alpak +6 more
doaj +1 more source
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Comorbid depression is a significant negative predictor of survival in patients with head and neck cancer (HNC). Prior studies have shown a prevalence of up to 40.1%; however, depression is often underdiagnosed in this patient population. Study Design Retrospective cohort. Setting Single‐institution database.
Sindhura Sridhar +8 more
wiley +1 more source
Leptin and psychiatric illnesses: does leptin play a role in antipsychotic-induced weight gain?
Lipids in Health and Disease, 2020 Antipsychotic-induced weight gain is the most prevalent somatic adverse event occurring in patients treated by antipsychotics, especially atypical antipsychotics.
Francky Teddy Endomba +3 more
doaj +1 more source
Olanzapine Attenuates Cue-elicited Craving for Tobacco
, 2004 Rationale: Recent biological conceptualizations of craving and addiction have implicated mesolimbic dopamine activity as a central feature of the process of addiction. Imaging, and pharmacological studies have supported a role for dopaminergic structures
Hutchinson, Kent E +5 more
core
Risk of Mortality (including Sudden Cardiac Death) and Major Cardiovascular Events in Users of Olanzapine and Other Antipsychotics: A Study with the General Practice Research Database. [PDF]
, 2013 Objective. Assess risk of cardiac events and mortality among users of olanzapine and other antipsychotics relative to nonusers. Methods. The General Practice Research Database was used to identify cohorts of antipsychotic users and nonusers with ...
Brunner, Elizabeth +8 more
core +3 more sources
Pediatric Investigation, EarlyView.The current study was among the first clinical trials that combined dance movement therapy (DMT) and pharmacotherapy to enhance self‐esteem and alleviate anxious and depressive symptoms in adolescents with major depressive disorder. Results indicated that DMT combined with pharmacotherapy improved depression symptoms more than pharmacotherapy alone ...
Yanru Liu +7 more
wiley +1 more source