Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine
This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan +24 more
wiley +1 more source
Comparative diagnostic accuracy of the triglyceride/HDL-c ratio and lipid accumulation product index for the early detection of metabolic syndrome among adults with obesity in Indonesia: findings from the 2023 Health Survey. [PDF]
Alvitananda AA +4 more
europepmc +1 more source
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu +6 more
wiley +1 more source
Association of Serum Glucose/Potassium Ratio with Injury Severity and Transfusion Requirements in Traumatic Pelvic Fractures: A Retrospective Cohort Study. [PDF]
Sahin AA, Özbilen YE, Akalın Ç.
europepmc +1 more source
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen +8 more
wiley +1 more source
Lung ultrasound score ≥ 6 predicts surfactant administration decisions in meconium aspiration syndrome: a multicenter prospective study. [PDF]
Chen Q +11 more
europepmc +1 more source
Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin +19 more
wiley +1 more source
First-Trimester Gestational Diabetes Mellitus Risk Prediction with Machine Learning Techniques: Results from the BORN2020 Cohort Study. [PDF]
Pazaras N +9 more
europepmc +1 more source
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao +18 more
wiley +1 more source

