Results 141 to 150 of about 1,283,507 (343)

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

open access: yesAdvanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang   +10 more
wiley   +1 more source

"Social Informatics" within the System of Economic Education

open access: yesСтатистика України, 2015
Because transition from industrial to information society is a dominant tendency of the contemporary civilization, the great many explicitly practical questions arise: What are the new opportunities for humans in the information society?
V. V. Kozlov   +2 more
doaj  

Framework for Evaluation of the IT&C Audit Metrics Impact [PDF]

open access: yes
The paper defines an assessment system for performance of IT&C audit process. The analytical models of performance indicators are provided together with the interpretation of their results.
Marius POPA
core  

Pressure‐Induced Ultralow Critical Micelle Concentration of Surfactant for Encapsulating Dye

open access: yesAdvanced Science, EarlyView.
Ultralow critical micelle concentration (CMC) is successfully achieved by pressure. Compared to 917.2 ± 8.7 µm for cetyl trimethyl ammonium bromide at 0.10 MPa, the ultralow CMC at 0.80 GPa is a ≈111‐fold reduction for 8.3 ± 0.1 µm. The detection of ultralow CMC under pressure is owed to the pressure‐induced fluorescence quenching of the coumarin 35 ...
Qi Li   +7 more
wiley   +1 more source

Benchmarking the production of audit services: An efficiency frontier approach [PDF]

open access: yes
To compete effectively in an increasingly competitive audit market audit firms need information on the efficiency of the audit services they offer. This study reports on the cost and labor efficiency for a sample of 114 audit engagements conducted by one
Maijoor,S, Schelleman,C
core   +1 more source

Audit Switching and Audit Tenure as Determinants of Audit Quality

open access: yesJournal of Economics, Finance And Management Studies
This research aims to obtain empirical evidence of the effect of auditor switching and audit tenure on audit quality. This research was conducted on all companies listed on the Indonesia Stock Exchange for the 2020-2024 period. The sampling method uses purposive sampling. The total sample for this research was 215 companies. Audit quality in this study
Ni Made Wirasyanti Dwi Pratiwi   +3 more
openaire   +2 more sources

MoS2 Channel‐Enhanced High‐Density Charge Trap Flash Memory and Machine Learning‐Assisted Sensing Methodologies for Memory‐Centric Computing Systems

open access: yesAdvanced Science, EarlyView.
Driven by AI computing demands, this study investigates MoS2 channels for 3D NAND Flash to achieve high‐density, low‐power, and reliable nonvolatile memory. MoS2 enables a large memory window and lower operating voltages with low‐k tunneling layer, demonstrating endurance of 10⁴ cycles and retention of 10⁵ s. Comprehensive analyses and machine learning‐
Ki Han Kim   +7 more
wiley   +1 more source

RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice

open access: yesAdvanced Science, EarlyView.
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang   +7 more
wiley   +1 more source

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