Results 221 to 230 of about 129,683 (309)

Research progress on biomarkers of traumatic brain injury

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen   +8 more
wiley   +1 more source

3‐Deoxy‐3‐Fluoro Mannuronic Acid Alginates: Stereoselective Automated Synthesis and Conformational Behaviour

open access: yesAngewandte Chemie, EarlyView.
The impact of C‐3 fluorination on the synthesis and conformation of alginate oligosaccharides is investigated. A C‐3‐fluoro mannuronic acid building block is generated and shown to react with high β‐selectivity. Automated glycan assembly enables access to uniquely fluorinated mannuronic acid alginates where deoxyfluorination is shown not to perturb the
Sean T. Evans   +10 more
wiley   +2 more sources

Genetic prediction of blood cell reactivity and its potential causal influence on bone continuity and density disorders

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We applied Mendelian randomization to explore causal links between blood cell traits and skeletal disorders. Using genetic instruments from large‐scale summary statistics, we assessed effects on bone continuity, density, and structural integrity. Sensitivity and reverse analyses confirmed robust associations, highlighting potential shared biological ...
Zhiqin Deng   +8 more
wiley   +1 more source

Specific Ion Effects of Chaotropic and Superchaotropic Anions Probed by Raman Hydration‐Shell Spectroscopy

open access: yesAngewandte Chemie, EarlyView.
The vibrational frequencies of “dangling” water O─H bonds can be determined by Raman hydration‐ shell spectroscopy and used to differentiate chaotropes from kosmotropes and hydrophobes. Dangling O─H bonds are also detected around superchaotropic anions of the borate cluster type (B12X122−; X = H, F, Cl, Br, and I) but their frequencies do not directly ...
Werner M. Nau   +6 more
wiley   +2 more sources

Animal models in molecular biology research: Challenges, ethical imperatives, and the path to human‐relevant translation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi   +6 more
wiley   +1 more source

Quantitative Photo‐Reforming of Biomass to CO Spurred by In Situ Protonation of Carbon Dioxide Radical Anions

open access: yesAngewandte Chemie, EarlyView.
A “two‐in‐one” photoreduction strategy enabled by electron‐rich yolk Cd species both remote from and adjacent to sulfur vacancies is delivered to be ultraselective for the reduction of O2 and •CO2− in situ formed on the shell Bi2S3 composition (hole) by water oxidation and oxidative C–C cleavage of various biomass organic acids, furnishing CO with > 99%
Tengyu Liu   +5 more
wiley   +2 more sources

Metal‐free Hydrogen Generation from Seawater and Silicon Waste: A Circular Approach

open access: yesAngewandte Chemie, EarlyView.
Hydrogen was rapidly generated directly from untreated seawater and polymeric Si waste without any transition metal catalyst. The in situ generated polymeric cross‐linked Si resin was completely depolymerized under mild conditions into chloro‐silane monomers.
Mustapha Hamdaoui   +6 more
wiley   +2 more sources

Audit of antibiotic prescribing practices for pediatric pneumonia in the outpatient department: focus on amoxicillin and azithromycin. [PDF]

open access: yesBMC Infect Dis
Ahmed W   +10 more
europepmc   +1 more source

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