ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source
Decentralized Tele-Rehabilitation via Edge AI-Oracle Architecture for Spatiotemporal Pain Assessment. [PDF]
Bilous N +3 more
europepmc +1 more source
Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi +6 more
wiley +1 more source
ReFaceX: donor-driven reversible face anonymisation with detached recovery. [PDF]
Muhammad D +3 more
europepmc +1 more source
Lead auditors, their client portfolios and performances
Avhandlingen fokuserar på skillnader i klientportföljer och prestation mellan ansvariga (alternativt påskrivande) revisorer och består av fyra huvudsakliga delar (alternativt studier). I den första delen kopplas mått på professionell skepticism, som bygger på enkätsvar från ansvariga revisorer, till prestation.
openaire +1 more source
Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay +15 more
wiley +1 more source
SafeCodeRL: Security-Constrained Multi-Agent Reinforcement Learning for Trustworthy LLM-Generated IoT/CPS Software. [PDF]
Wang Z, Chen J, Wei Z, Lin L, Tong G.
europepmc +1 more source
Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse +13 more
wiley +1 more source
A privacy-preserving cloud storage framework with hybrid encryption, homomorphic keyword search, and blockchain-based integrity verification. [PDF]
Ahmed HMA, Zubair S, Tawfik M, Tawfik M.
europepmc +1 more source
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source

