Results 191 to 200 of about 582,638 (386)
This study examines the effects of Shank3 mutation on the mesoaccumbens pathway using a Shank3‐deficient rat model. The findings reveal altered social reward processing in these rats, accompanied by changes in dopaminergic and GABAergic neural activity within the ventral tegmental area (VTA) and dopamine release in the nucleus accumbense (NAc ...
Marie Barbier+4 more
wiley +1 more source
A NEW MODE OF DETECTING STONE IN THE BLADDER: THE AUDITORY METHOD. [PDF]
James McKenzie Davidson
openalex +1 more source
Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT
Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.
Bowei Li+8 more
wiley +1 more source
Chronic social stress elevates oxytocin levels, leading to immunosuppression by enhancing regulatory T‐cell activity and promoting anti‐inflammatory macrophage polarization in the spleen. Blocking oxytocin signaling reverses these effects but worsens stress‐induced behavioral disorders and reduces survival rates. This highlights oxytocin's dual role in
Yi‐Shu Zhang+5 more
wiley +1 more source
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge+16 more
wiley +1 more source
Piezoresistive Effect: A New Concept for Hearing Aids
An MXene/PVA sound sensor utilizing piezoresistive effects has been proposed with a detection limit of 60 dB and a frequency response of 20–4000 Hz, which is comparable to the performance of commercial hearing aids. By combining the sensor with machine learning, the accuracy rate of voiceprint recognition of wildlife conservation can reach up to 99 ...
Mengyao Gao+8 more
wiley +1 more source
Many people with hearing loss struggle to understand speech in noisy environments, making noise robustness critical for hearing-assistive devices. Recently developed haptic hearing aids, which convert audio to vibration, can improve speech-in-noise ...
Mark D. Fletcher+4 more
doaj +1 more source