Results 131 to 140 of about 924,600 (401)

Pre-stimulus influences on auditory perception arising from sensory representations and decision processes [PDF]

, 2016
The qualities of perception depend not only on the sensory inputs but also on the brain state before stimulus presentation. Although the collective evidence from neuroimaging studies for a relation between prestimulus state and perception is strong, the ...
Kayser, Christoph, Kayser, Stephanie J., McNair, Steven W.   +2 more
core   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source

A synaptic and circuit basis for corollary discharge in the auditory cortex

Nature, 2014
Sensory regions of the brain integrate environmental cues with copies of motor-related signals important for imminent and ongoing movements. In mammals, signals propagating from the motor cortex to the auditory cortex are thought to have a critical role ...
D. Schneider, Anders Nelson, R. Mooney
semanticscholar   +1 more source

Exploration of Novel Biomarkers Through a Precision Medicine Approach Using Multi‐Omics and Brain Organoids in Patients With Atypical Depression and Psychotic Symptoms

Advanced Science, EarlyView.
This study examines major depressive disorder with atypical features and psychotic symptoms through a multi‐omics precision medicine approach. By integrating clinical assessments, WBC scRNA‐seq, plasma proteomics, and brain organoid models, it uncovers immune dysregulation, synaptic protein alterations, and stress‐sensitive neuronal changes.
Insook Ahn, Soyeon Chang, Jiyoung Lee, Seok‐Ho Choi, Jinju Han, Yangsik Kim   +5 more
wiley   +1 more source

Auditory Connections and Functions of Prefrontal Cortex

Frontiers in Neuroscience, 2014
The functional auditory system extends from the ears to the frontal lobes with successively more complex functions occurring as one ascends the hierarchy of the nervous system.
Bethany ePlakke, Lizabeth M Romanski
doaj   +1 more source

Silent reading of direct versus indirect speech activates voice-selective areas in the auditory cortex [PDF]

, 2011
In human communication, direct speech (e.g., Mary said: “I'm hungry”) is perceived to be more vivid than indirect speech (e.g., Mary said [that] she was hungry). However, for silent reading, the representational consequences of this distinction are still
Belin, P., Scheepers, C., Yao, B.
core   +2 more sources

Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways

Advanced Science, EarlyView.
Decoding sound from neural activity in mice reveals a striking shift in how the brain encodes sound: from precise but redundant timing codes in early auditory areas to efficient, synergistic rate‐based codes in the cortex. This transformation highlights a robust neural strategy for turning complex acoustic input into coherent perception across the ...
Alexa Buck, Typhaine Dupont, Rupert Andrews Cavanagh, Olivier Postal, Jérôme Bourien, Jean‐Luc Puel, Nicolas Michalski, Boris Gourévitch   +7 more
wiley   +1 more source

Eye Movement-Related Activity in and below the Macaque Auditory Cortex

i-Perception, 2011
Recent studies have revealed influences of viewing scenes on sound processing and of gaze direction on sound location coding in the auditory cortex of the macaque monkey. We examined the spontaneous activity of auditory cortex in the darkness.
Yoshinao Kajikawa, Charles Schroeder
doaj   +1 more source

Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders. [PDF]

, 2015
BackgroundAutism spectrum disorders (ASDs) likely involve dysregulation of multiple genes related to brain function and development. Abnormalities in individual regulatory small non-coding RNA (sncRNA), including microRNA (miRNA), could have profound ...
Ander, Bradley P, Barger, Nicole, Schumann, Cynthia M, Sharp, Frank R, Stamova, Boryana   +4 more
core   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source