Results 171 to 180 of about 7,669 (292)

Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models

Pediatric Discovery, EarlyView.
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou, Christopher L.‐H. Huang, Ying Yang, Yanmin Zhang   +3 more
wiley   +1 more source

The transformative potential of artificial intelligence in pediatric medicine: Current applications, methodological challenges, and future directions

Pediatric Investigation, EarlyView.
Artificial intelligence (AI) offers transformative potential for paediatric diagnosis and treatment, yet implementation faces unique challenges, including data scarcity, algorithmic bias, and children's developmental physiology. This review examines current applications and charts a path toward transparent, equitable, and trustworthy AI in child health.
Ruisong Wang, Xiaoman Ding, Wanyue Zhang, Tieliu Shi   +3 more
wiley   +1 more source

Rhyming in the cold: first evidence of soniferous fishes in the Southern Ocean

Remote Sensing in Ecology and Conservation, EarlyView.
The acoustic ecology of Southern Ocean fishes remains unknown due to a lack of dedicated acoustic research on the fishes of this ocean. Passive acoustic monitoring data were collected at the South African sub‐Antarctic Prince Edward Islands using an underwater acoustic recorder, and towed underwater Ski‐Monkey cameras were deployed to identify fish ...
Fannie W. Shabangu, Grant van der Heever, Charles von der Meden, Hannah Truter, Stephen J. Lamberth, Ofer Gon   +5 more
wiley   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Improved Bone Conduction and Hearing Outcomes After Stapes Surgery for Otosclerosis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To evaluate the improvement in bone conduction (BC) thresholds after stapes surgery for otosclerosis, compare the outcomes of surgical techniques, and analyze the short‐ and long‐term results to inform treatment strategies. Methods We retrospectively reviewed data from 173 patients (188 ears) who underwent total stapedectomy, partial
Na Zhang, Xiao‐Bo Ma, Dan‐Ni Wang, Yi Li, Yan Zheng, Yong‐Xin Li, Shou‐Qin Zhao   +6 more
wiley   +1 more source

Comorbidity Patterns Between Hearing Loss and Symptomatic Dizziness in Middle‐Aged and Older Adults

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To explore the comorbidity patterns between hearing loss and symptomatic dizziness (HL‐SD) in middle‐aged and older adults. Methods This cross‐sectional study used data from the 1999 to 2004 National Health and Nutrition Examination Survey (NHANES). After excluding incomplete data, 2961 participants aged 40–69 were analyzed. Logistic
Chun‐Yan Liu, Xiao‐Nan Wu, Jin Li, Jiao Zhang, Yun Gao, Da‐Yong Wang, Qiu‐Ju Wang   +6 more
wiley   +1 more source

Extensive Subcutaneous Emphysema and Pneumomediastinum Following Eustachian Tube Dilation and PET Insertion: A Rare Complication

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Eustachian tube dilation (ETD) is an increasingly popular and seemingly safe method of treating ETD. We present a rare case of subcutaneous emphysema and pneumomediastinum following ETD. Methods Retrospective chart review. Patient consent was obtained for data collection, analysis, drafting, and publication of information ...
Mihai A. Bentan, Nam K. Lee, Scott E. Mann, Emily Ambrose   +3 more
wiley   +1 more source

Epac1 Alleviates Senescence in Auditory Hair Cells via the Ferroptosis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives The aim of this study was to investigate the changes in Epac1 and ferroptosis‐related proteins in aged mice and the House Ear Institute‐Organ of Corti 1 (HEI‐OC1) cells, with the goal of elucidating their potential role in age‐related hearing loss. Methods The expression of Epac1 in the cochlea of C57BL/6J mice was examined by using
Wen‐Jun An, Chen‐Yu Xu, Meng‐Ya Shen, Xiao‐Tao Guo, Chun‐Chen Pan, Jing‐Wu Sun, Xiao‐Min Tang, Jia‐Qiang Sun   +7 more
wiley   +1 more source

Audiological Characteristics in Vestibular Schwannoma Patients

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Vestibular schwannoma (VS) is a benign tumor that originates from the Schwann cells of the vestibular nerve sheath in the internal auditory canal. This retrospective study collected data from patients with VS who underwent surgical treatment to identify their demographic characteristics and audiometric features.
Shan Zeng, Yi‐Yun Lou, Hui‐Qian Yu, Wei‐Dong Zhao, Wen‐Yan Li   +4 more
wiley   +1 more source

Advances in prenatal ultrasound diagnosis of fetal tympanic ring anomalies. [PDF]

Front Med (Lausanne)
Zhang H, Liao R, Li Y, Huang F, Li L, Lyu G.   +5 more
europepmc   +1 more source