Results 141 to 150 of about 2,311,278 (308)

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

Advanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen, Yu‐Xuan Weng, Zhi‐Xuan Xia, Yue‐Ling Zhao, Qian‐Qian Ding, Si‐Ying Wang, Ting Cao, Xuan‐Ying Chen, Wu‐Cheng Tao, Shen Lin, Zhou Chen, Yi‐Xiao Luo   +11 more
wiley   +1 more source

Exploring the Correlation between Binaural Processing Abilities and Auditory Processing Domains Questionnaire Scores in Children with Specific Learning Disabilities

Auditory and Vestibular Research
Background and Aim: A Specific Learning Disability (SLD) is a neurological disorder thought to arise from dysfunctions within the central nervous system.
Marziyeh Moallemi, Nariman Rahbar, Mohsen Ahadi, Mohammad Maarefvand   +3 more
doaj   +1 more source

Sensory auditory processing and intuitive sound detection : an investigation of musical experts and nonexperts [PDF]

, 2006
The auditory system can detect occasional changes (deviants) in acoustic regularities without the need for subjects to focus their attention on the sound material.
van Zuijen, Titia
core  

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

Advanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba, Jinyoung Park, Achal Duhoon, Cao Thuy Giang Nguyen, Nitu Bhaskar, Sumanta Kumar Karan, Hasan Akbaba, Parbeen Singh, Thi Bao Tram Tran, Yuhui Zhu, Zhiming Li, I'jaaz Muhammad, Xiaojun Zhang, Hoang Quan Truong, A. Daniel Davidar, Elizabeth Schmitzer, Vikas N. Vattipally, Angelica F. Lopez, Patrick Kramer, Victor M. Quiroz, Ben Bykov, Claire Hao, Amir Manbachi, Nicholas Theodore, Joshua C. Doloff, Thanh D. Nguyen   +25 more
wiley   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Ad-hoc synthesis of auditory icons [PDF]

, 1998
Presented at 5th International Conference on Auditory Display (ICAD), Glasgow, UK, November 1-4, 1998.This article introduces ad-hoc synthesis, an approach to designing auditory icons and synthesis algorithms that emphasizes the perception of the sounds ...
Conversy, Stephane
core  

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

Case Report: Improved sound perception following auditory management of central auditory processing disorder complicating bitemporal strokes

Frontiers in Audiology and Otology
IntroductionThis case report describes the potential benefits of auditory training and management for acquired central auditory processing disorder (CAPD), suggesting neuroplasticity and rehabilitation potential in a 57-year-old stroke patient.MethodsThe
Dominic Sze Ho Ip, Cristina Ferraz Borges Murphy, Doris-Eva Bamiou, Doris-Eva Bamiou   +3 more
doaj   +1 more source

The Influence of Presentation Speed and Spatial Location on Reaction Time to Auditory Displays [PDF]

, 2007
Presented at the 13th International Conference on Auditory Display (ICAD2007) June 26-29, 2007 in Montréal, Canada.To gain a better understanding of what parameters influence the redirection of attention to auditory stimuli, principal spatiotemporal ...
Roginska, Agnieszka
core  

ORBIT‐AMD: Ordinal Risk, Bilateral Imaging, and Trajectory Learning for Age‐Related Macular Degeneration in Multi‐Cohorts

Advanced Science, EarlyView.
Eligibility flow and real‐world AMD burden in the UKB retinal imaging cohort and TMUEH external‐validation cohort. Overview of the ORBIT‐AMD architecture, integrating retinal representation pretraining, bilateral eye‐graph modeling and concept bottleneck learning to support ordered risk, bilateral context, interpretable lesion concepts, longitudinal ...
Xuehao Cui, Dejia Wen, Patrick Yu‐Wai‐Man, Xiaorong Li   +3 more
wiley   +1 more source